产品: FXYD2 抗体
货号: DF9941
描述: Rabbit polyclonal antibody to FXYD2
应用: WB IHC
反应: Human, Mouse
预测: Chicken
分子量: 7 kDa; 7kD(Calculated).
蛋白号: P54710
RRID: AB_2843135

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse
预测:
Chicken(88%)
克隆:
Polyclonal
特异性:
FXYD2 Antibody detects endogenous levels of total FXYD2.
RRID:
AB_2843135
引用格式: Affinity Biosciences Cat# DF9941, RRID:AB_2843135.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Sodium potassium ATPase, gamma-1 polypeptide; ATP 1C; ATP1 C; ATP1 G1; ATP1C; ATP1G 1; ATP1G1; ATPase, Na+/K+ transporting, gamma 1 polypeptide; FXYD 2; FXYD domain containing ion transport regulator 2; Gamma subunit of sodium potassium ATPase; GNAKATP; HOMG 2; HOMG2; Hypomagnesemia 2, renal; Na(+)/K(+) ATPase subunit gamma; Sodium potassium ATPase, gamma polypeptide; Sodium pump gamma chain; Sodium/potassium-transporting ATPase gamma chain; sodium/potassium-transporting ATPase subunit gamma;

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
表达:
P54710 ATNG_HUMAN:

Expressed in the distal convoluted tubule in the kidney. Found on basolateral membranes of nephron epithelial cells.

序列:
MTGLSMDGGGSPKGDVDPFYYDYETVRNGGLIFAGLAFIVGLLILLSRRFRCGGNKKRRQINEDEP

种属预测

种属预测:

score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。

Species
Results
Score
Chicken
88
Dog
67
Pig
0
Horse
0
Bovine
0
Sheep
0
Xenopus
0
Zebrafish
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - P54710 作为底物

Site PTM Type Enzyme

研究背景

功能:

May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase.

细胞定位:

Membrane>Single-pass type III membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Expressed in the distal convoluted tubule in the kidney. Found on basolateral membranes of nephron epithelial cells.

亚基结构:

Regulatory subunit of the sodium/potassium-transporting ATPase which is composed of a catalytic alpha subunit, an auxiliary non-catalytic beta subunit and an additional regulatory subunit.

蛋白家族:

Belongs to the FXYD family.

研究领域

· Environmental Information Processing > Signal transduction > cGMP-PKG signaling pathway.   (View pathway)

· Environmental Information Processing > Signal transduction > cAMP signaling pathway.   (View pathway)

· Organismal Systems > Circulatory system > Cardiac muscle contraction.   (View pathway)

· Organismal Systems > Circulatory system > Adrenergic signaling in cardiomyocytes.   (View pathway)

· Organismal Systems > Endocrine system > Insulin secretion.   (View pathway)

· Organismal Systems > Endocrine system > Thyroid hormone synthesis.

· Organismal Systems > Endocrine system > Thyroid hormone signaling pathway.   (View pathway)

· Organismal Systems > Excretory system > Aldosterone-regulated sodium reabsorption.

· Organismal Systems > Excretory system > Endocrine and other factor-regulated calcium reabsorption.

· Organismal Systems > Excretory system > Proximal tubule bicarbonate reclamation.

· Organismal Systems > Digestive system > Salivary secretion.

· Organismal Systems > Digestive system > Pancreatic secretion.

· Organismal Systems > Digestive system > Carbohydrate digestion and absorption.

· Organismal Systems > Digestive system > Protein digestion and absorption.

· Organismal Systems > Digestive system > Mineral absorption.

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