产品: SLC9A1 抗体
货号: DF9933
描述: Rabbit polyclonal antibody to SLC9A1
应用: WB IHC IF/ICC
文献验证: WB, IHC
反应: Human, Mouse, Rat, Monkey
预测: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
蛋白号: P19634
RRID: AB_2843127

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat, Monkey
克隆:
Polyclonal
特异性:
SLC9A1 Antibody detects endogenous levels of total SLC9A1.
RRID:
AB_2843127
引用格式: Affinity Biosciences Cat# DF9933, RRID:AB_2843127.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

amiloride-sensitive; APNH; APNH1; FLJ42224; Na Li countertransporter; Na(+)/H(+) antiporter; Na(+)/H(+) exchanger 1; Na+ H+ antiporter amiloride-sensitive; Na+ H+ antiporter; Na+ H+ exchanger 1; NHE-1; NHE1; OTTHUMP00000004468; SL9A1_HUMAN; SLC9A1; Sodium hydrogen exchanger 1; Sodium/hydrogen exchanger 1; solute carrier family 9; Solute carrier family 9 member 1; Solute carrier family 9 sodium hydrogen exchanger isoform 1 antiporter Na+ H+ amiloride sensitive; Solute carrier family 9 subfamily A (NHE1 cation proton antiporter 1) member 1; Solute carrier family 9 subfamily A member 1;

抗原和靶标

免疫原:

A synthesized peptide derived from human SLC9A1, corresponding to a region within the internal amino acids.

基因/基因ID:

研究领域

· Cellular Processes > Cell motility > Regulation of actin cytoskeleton.   (View pathway)

· Environmental Information Processing > Signal transduction > cAMP signaling pathway.   (View pathway)

· Environmental Information Processing > Signal transduction > Apelin signaling pathway.   (View pathway)

· Human Diseases > Cancers: Overview > Proteoglycans in cancer.

· Organismal Systems > Circulatory system > Cardiac muscle contraction.   (View pathway)

· Organismal Systems > Circulatory system > Adrenergic signaling in cardiomyocytes.   (View pathway)

· Organismal Systems > Endocrine system > Thyroid hormone signaling pathway.   (View pathway)

· Organismal Systems > Digestive system > Salivary secretion.

· Organismal Systems > Digestive system > Gastric acid secretion.

· Organismal Systems > Digestive system > Pancreatic secretion.

文献引用

1). Targeting macrophage to myofibroblast transition by circ_0001103 for subretinal fibrosis treatment. Journal of translational medicine, 2025 (PubMed: 40022123) [IF=7.4]

2). Cardioprotective role of A-cycloglycosylated derivative of Rubiadin in diabetic cardiomyopathy in rats. International Immunopharmacology, 2023 (PubMed: 36989899) [IF=4.8]

3). Neuroprotective effect of Na+/H+ exchangers isoform‐1 inactivation against 6‐hydroxydopamine‐induced mitochondrial dysfunction and neuronal apoptosis in Parkinson's disease models. DRUG DEVELOPMENT RESEARCH, 2021 (PubMed: 33538000) [IF=3.5]

4). Potential Therapeutic Effect of Citronellal on Diabetic Cardiomyopathy in Experimental Rats. Evidence-based Complementary and Alternative Medicine, 2021 (PubMed: 34840590)

Application: IHC    Species: Rat    Sample: myocardial tissues

Figure 4 CT repressing the apoptosis of DCM rat cardiomyocytes by influencing the expression of NHE1 protein. (a) Representative immunohistochemical staining of NHE1 expression in each group. (b) Representative immunofluorescence staining of Bcl-2 and Bax expression, respectively. (c) Western blot analysis of NHE1, Bcl-2, and Bax expression, respectively. (d) The quantitative analysis of the expression of NHE1, Bcl-2, and Bax, respectively. n = 6 per group. Data are mean ± SD; ∗p < 0.05 vs. the control group; #p < 0.05 vs. the DCM group; ns, not significant.

Application: WB    Species: Rat    Sample: myocardial tissues

Figure 4 CT repressing the apoptosis of DCM rat cardiomyocytes by influencing the expression of NHE1 protein. (a) Representative immunohistochemical staining of NHE1 expression in each group. (b) Representative immunofluorescence staining of Bcl-2 and Bax expression, respectively. (c) Western blot analysis of NHE1, Bcl-2, and Bax expression, respectively. (d) The quantitative analysis of the expression of NHE1, Bcl-2, and Bax, respectively. n = 6 per group. Data are mean ± SD; ∗p < 0.05 vs. the control group; #p < 0.05 vs. the DCM group; ns, not significant.

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