SH3BGRL3 Antibody - #DF9905

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产品: SH3BGRL3 抗体
货号: DF9905
描述: Rabbit polyclonal antibody to SH3BGRL3
应用: WB IHC
文献验证:
反应: Human, Mouse, Rat
预测: Pig, Bovine, Horse, Rabbit, Dog, Chicken
分子量: 10 kDa; 10kD(Calculated).
蛋白号: Q9H299
RRID: AB_2843099

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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MS Report
HPLC Report
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说明书
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实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
预测:
Pig(100%), Bovine(%), Horse(%), Rabbit(%), Dog(%), Chicken(%)
克隆:
Polyclonal
特异性:
SH3BGRL3 Antibody detects endogenous levels of total SH3BGRL3.
RRID:
AB_2843099
引用格式: Affinity Biosciences Cat# DF9905, RRID:AB_2843099.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

epididymis secretory protein Li 297; HEL-S-297; SH3 domain binding glutamic acid rich protein like 3; SH3 domain-binding glutamic acid-rich-like protein 3; SH3 domain-binding protein 1; Sh3bgrl3; SH3BGRL3 like protein; SH3BP-1; SH3L3_HUMAN; TIP B1; TIP-B1; TNF inhibitory protein;

抗原和靶标

免疫原:
Uniprot:

Q9H299(SH3L3_HUMAN) >>Visit HPA database.

基因/基因ID:
SH3BGRL3(83442)
表达:
Q9H299 SH3L3_HUMAN:

Ubiquitous.

序列:
MSGLRVYSTSVTGSREIKSQQSEVTRILDGKRIQYQLVDISQDNALRDEMRALAGNPKATPPQIVNGDQYCGDYELFVEAVEQNTLQEFLKLA

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Dog
100
Rabbit
100
Chicken
92
Zebrafish
69
Xenopus
62
Sheep
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

研究背景

功能:

Could act as a modulator of glutaredoxin biological activity.

细胞定位:

Cytoplasm. Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Ubiquitous.

蛋白家族:

Belongs to the SH3BGR family.

文献引用

1). Differential expression of serum proteins before 20 weeks gestation in women with hypertensive disorders of pregnancy: A potential role for SH3BGRL3. Placenta, 2021 (PubMed: 33217630) [IF=3.0]

Application: IF/ICC    Species: Human    Sample: placenta tissue

Fig. 2. Median serum levels of (A) endoglin and (B) SH3BGRL3 before 20 weeks gestation in women who experienced an uncomplicated pregnancy and women who later developed HDP by quantitative proteomics (***P < 0.001). C: Confocal microscope images of anti-SH3BGRL3 in placenta tissue. The immunoreactivity of SH3BGRL3 (red) was higher in HDP patients compared to normal pregnancies. Cell nuclei were stained with DAPI (blue). Original magnification 40 × .

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