SRR Antibody - #DF9882

(6)  
产品: SRR 抗体
货号: DF9882
描述: Rabbit polyclonal antibody to SRR
应用: WB IHC
反应: Human, Mouse, Rat
预测: Pig, Horse
分子量: 37 kDa; 37kD(Calculated).
蛋白号: Q9GZT4
RRID: AB_2843076

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Pig(90%), Horse(80%)
克隆:
Polyclonal
特异性:
SRR Antibody detects endogenous levels of total SRR.
RRID:
AB_2843076
引用格式: Affinity Biosciences Cat# DF9882, RRID:AB_2843076.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

D serine ammonia lyase; D serine dehydratase; D-serine ammonia-lyase; D-serine dehydratase; ILV1; ISO1; L serine ammonia lyase; L serine dehydratase; L-serine ammonia-lyase; L-serine dehydratase; Serine racemase; srr; SRR_HUMAN;

抗原和靶标

免疫原:
Uniprot:

Q9GZT4(SRR_HUMAN) >>Visit HPA database.

基因/基因ID:
SRR(63826)
表达:
Q9GZT4 SRR_HUMAN:

Brain: expressed at high levels in hippocampus and corpus callosum, intermediate levels in substantia nigra and caudate, and low levels in amygdala, thalamus, and subthalamic nuclei. Expressed in heart, skeletal muscle, kidney and liver.

序列:
MCAQYCISFADVEKAHINIRDSIHLTPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGALNAVRSLVPDALERKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPDCKKLAIQAYGASIVYCEPSDESRENVAKRVTEETEGIMVHPNQEPAVIAGQGTIALEVLNQVPLVDALVVPVGGGGMLAGIAITVKALKPSVKVYAAEPSNADDCYQSKLKGKLMPNLYPPETIADGVKSSIGLNTWPIIRDLVDDIFTVTEDEIKCATQLVWERMKLLIEPTAGVGVAAVLSQHFQTVSPEVKNICIVLSGGNVDLTSSITWVKQAERPASYQSVSV

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Pig
90
Horse
80
Bovine
70
Rabbit
70
Sheep
60
Dog
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q9GZT4 作为底物

Site PTM Type Enzyme
K45 Ubiquitination
K51 Ubiquitination
K56 Methylation
K56 Ubiquitination
C113 S-Nitrosylation
S134 Phosphorylation
K205 Ubiquitination
Y207 Phosphorylation
S212 Phosphorylation
C217 S-Nitrosylation
Y218 Phosphorylation
S220 Phosphorylation
K221 Ubiquitination
K225 Ubiquitination
S242 Phosphorylation
S339 Phosphorylation

研究背景

功能:

Catalyzes the synthesis of D-serine from L-serine. D-serine is a key coagonist with glutamate at NMDA receptors. Has dehydratase activity towards both L-serine and D-serine.

翻译修饰:

S-nitrosylated, leading to decrease the enzyme activity.

组织特异性:

Brain: expressed at high levels in hippocampus and corpus callosum, intermediate levels in substantia nigra and caudate, and low levels in amygdala, thalamus, and subthalamic nuclei. Expressed in heart, skeletal muscle, kidney and liver.

亚基结构:

Homodimer.

蛋白家族:

Belongs to the serine/threonine dehydratase family.

研究领域

· Metabolism > Amino acid metabolism > Glycine, serine and threonine metabolism.

· Metabolism > Global and overview maps > Metabolic pathways.

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