RND2 Antibody - #DF9867

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产品: RND2 抗体
货号: DF9867
描述: Rabbit polyclonal antibody to RND2
应用: WB IHC
反应: Human, Mouse, Rat
预测: Pig, Bovine, Horse, Sheep, Rabbit, Dog
分子量: 25 kDa; 25kD(Calculated).
蛋白号: P52198
RRID: AB_2843061

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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MS Report
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说明书
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实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
预测:
Pig(92%), Bovine(%), Horse(%), Sheep(%), Rabbit(%), Dog(%)
克隆:
Polyclonal
特异性:
RND2 Antibody detects endogenous levels of total RND2.
RRID:
AB_2843061
引用格式: Affinity Biosciences Cat# DF9867, RRID:AB_2843061.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

ARHN; CTD-3199J23.4; GTP-binding protein Rho7; ras homolog gene family, member N; Rho 7; Rho family GTPase 2; Rho N; Rho related GTP-binding protein RhoN; Rho-related GTP-binding protein Rho7; Rho-related GTP-binding protein RhoN; Rho7; RhoN; Rnd 2; Rnd2; RND2_HUMAN;

抗原和靶标

免疫原:
Uniprot:

P52198(RND2_HUMAN) >>Visit HPA database.

基因/基因ID:
RND2(8153)
表达:
P52198 RND2_HUMAN:

Highly expressed in testis.

序列:
MEGQSGRCKIVVVGDAECGKTALLQVFAKDAYPGSYVPTVFENYTASFEIDKRRIELNMWDTSGSSYYDNVRPLAYPDSDAVLICFDISRPETLDSVLKKWQGETQEFCPNAKVVLVGCKLDMRTDLATLRELSKQRLIPVTHEQGTVLAKQVGAVSYVECSSRSSERSVRDVFHVATVASLGRGHRQLRRTDSRRGMQRSAQLSGRPDRGNEGEIHKDRAKSCNLM

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Pig
92
Horse
92
Bovine
92
Sheep
92
Dog
92
Rabbit
92
Zebrafish
50
Xenopus
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

研究背景

功能:

May be specifically involved in neuronal and hepatic functions. Is a C3 toxin-insensitive member of the Rho subfamily (By similarity).

细胞定位:

Cytoplasmic vesicle>Secretory vesicle>Acrosome membrane>Lipid-anchor>Cytoplasmic side.
Note: Colocalizes with RACGAP1 in Golgi-derived proacrosomal vesicles and the acrosome.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Highly expressed in testis.

亚基结构:

Interacts with the Rho-GAP domain of RACGAP1. Interacts with UBXD5. Interacts with PRAG1 (By similarity).

蛋白家族:

Belongs to the small GTPase superfamily. Rho family.

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