| 产品: | RAB39A 抗体 |
| 货号: | DF9828 |
| 描述: | Rabbit polyclonal antibody to RAB39A |
| 应用: | WB IF/ICC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit |
| 分子量: | 25 kDa,37kDa; 25kD(Calculated). |
| 蛋白号: | Q14964 |
| RRID: | AB_2843022 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF9828, RRID:AB_2843022.
展开/折叠
rab related GTP binding protein; Rab-39; Rab39; RAB39A; RAB39A member RAS oncogene family; Ras related protein Rab39A; Ras-related protein Rab-39A; RB39A_HUMAN;
抗原和靶标
- Q14964 RB39A_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
METIWIYQFRLIVIGDSTVGKSCLLHRFTQGRFPGLRSPACDPTVGVDFFSRLLEIEPGKRIKLQLWDTAGQERFRSITRSYYRNSVGGFLVFDITNRRSFEHVKDWLEEAKMYVQPFRIVFLLVGHKCDLASQRQVTREEAEKLSADCGMKYIETSAKDATNVEESFTILTRDIYELIKKGEICIQDGWEGVKSGFVPNTVHSSEEAVKPRKECFC
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
研究背景
Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in vesicular trafficking. Plays a role in the fusion of phagosomes with lysosomes. Negatively regulates LPS-induced autophagosome formation in macrophages possibly by implicating PI3K. May be involved in multiple neurite formation (By similarity).
Cell membrane>Lipid-anchor>Cytoplasmic side. Cytoplasmic vesicle>Phagosome. Cytoplasmic vesicle>Phagosome membrane>Lipid-anchor>Cytoplasmic side. Lysosome.
Note: Recruited to phagosomes containing S.aureus or M.tuberculosis.
Interacts with BECN1. Probably associates with the PI3K (PI3KC3/PI3K-III/class III phosphatidylinositol 3-kinase) complex. Interacts with UACA (By similarity).
Belongs to the small GTPase superfamily. Rab family.
限制条款
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