| 产品: | RAB32 抗体 |
| 货号: | DF9825 |
| 描述: | Rabbit polyclonal antibody to RAB32 |
| 应用: | WB IHC |
| 反应: | Human, Mouse, Rat |
| 预测: | Horse, Rabbit |
| 分子量: | 25 kDa; 25kD(Calculated). |
| 蛋白号: | Q13637 |
| RRID: | AB_2843019 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF9825, RRID:AB_2843019.
展开/折叠
RAB32; RAB32, member RAS oncogene family; RAB32_HUMAN; Ras related protein Rab32; Ras-related protein Rab-32;
抗原和靶标
Widely expressed with high levels in heart, liver, kidney, bone marrow, testis, colon and fetal lung.
- Q13637 RAB32_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAGGGAGDPGLGAAAAPAPETREHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGVDFALKVLNWDSRTLVRLQLWDIAGQERFGNMTRVYYKEAVGAFVVFDISRSSTFEAVLKWKSDLDSKVHLPNGSPIPAVLLANKCDQNKDSSQSPSQVDQFCKEHGFAGWFETSAKDNINIEEAARFLVEKILVNHQSFPNEENDVDKIKLDQETLRAENKSQCC
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
研究背景
Acts as an A-kinase anchoring protein by binding to the type II regulatory subunit of protein kinase A and anchoring it to the mitochondrion. Also involved in synchronization of mitochondrial fission. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays an important role in the control of melanin production and melanosome biogenesis. In concert with RAB38, regulates the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes (By similarity).
Mitochondrion. Mitochondrion outer membrane>Lipid-anchor. Cytoplasmic vesicle>Phagosome. Cytoplasmic vesicle>Phagosome membrane>Lipid-anchor>Cytoplasmic side. Melanosome. Melanosome membrane.
Note: Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211). The BLOC-3 complex, a heterodimer of HPS1 and HPS4 promotes its membrane localization (PubMed:23084991).
Widely expressed with high levels in heart, liver, kidney, bone marrow, testis, colon and fetal lung.
Interacts with ANKRD27. A decreased interaction with ANKRD27 seen in the presence of SGSM2.
Belongs to the small GTPase superfamily. Rab family.
限制条款
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