| 产品: | RAB11FIP5 抗体 |
| 货号: | DF9796 |
| 描述: | Rabbit polyclonal antibody to RAB11FIP5 |
| 应用: | WB IHC |
| 反应: | Human, Mouse, Rat, Monkey |
| 预测: | Pig, Bovine, Horse, Dog |
| 分子量: | 70 kDa; 70kD(Calculated). |
| 蛋白号: | Q9BXF6 |
| RRID: | AB_2842990 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF9796, RRID:AB_2842990.
展开/折叠
GAF 1; Gaf-1; GAF1; gamma SNAP associated factor 1; Gamma-SNAP-associated factor 1; KIAA0857; Phosphoprotein pp75; pp75; RAB11 family interacting protein 5 (class I); Rab11 family-interacting protein 5; Rab11 FIP5; Rab11 interacting protein; Rab11 interacting protein Rip11; Rab11-FIP5; Rab11-interacting protein Rip11; Rab11fip5; RFIP5_HUMAN; RIP11;
抗原和靶标
Detected at low levels in heart, brain, placenta, lung, liver, adipocytes, kidney, spleen, skeletal muscle and pancreas.
- Q9BXF6 RFIP5_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MALVRGAEPAAGPSRWLPTHVQVTVLRARGLRGKSSGAGSTSDAYTVIQVGREKYSTSVVEKTHGCPEWREECSFELPPGALDGLLRAQEADAGPAPWAASSAAACELVLTTMHRSLIGVDKFLGQATVALDEVFGAGRAQHTQWYKLHSKPGKKEKERGEIEVTIQFTRNNLSASMFDLSMKDKPRSPFSKIRDKMKGKKKYDLESASAILPSSAIEDPDLGSLGKMGKAKGFFLRNKLRKSSLTQSNTSLGSDSTLSSASGSLAYQGPGAELLTRSPSRSSWLSTEGGRDSAQSPKLFTHKRTYSDEANQMRVAPPRALLDLQGHLDAASRSSLCVNGSHIYNEEPQGPVRHRSSISGSLPSSGSLQAVSSRFSEEGPRSTDDTWPRGSRSNSSSEAVLGQEELSAQAKVLAPGASHPGEEEGARLPEGKPVQVATPIVASSEAVAEKEGARKEERKPRMGLFHHHHQGLSRSELGRRSSLGEKGGPILGASPHHSSSGEEKAKSSWFGLREAKDPTQKPSPHPVKPLSAAPVEGSPDRKQSRSSLSIALSSGLEKLKTVTSGSIQPVTQAPQAGQMVDTKRLKDSAVLDQSAKYYHLTHDELISLLLQRERELSQRDEHVQELESYIDRLLVRIMETSPTLLQIPPGPPK
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q9BXF6 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| R5 | Methylation | Uniprot | |
| S116 | Phosphorylation | Uniprot | |
| T165 | Phosphorylation | Uniprot | |
| S174 | Phosphorylation | Uniprot | |
| S176 | Phosphorylation | Uniprot | |
| S181 | Phosphorylation | Uniprot | |
| S188 | Phosphorylation | Uniprot | |
| S191 | Phosphorylation | Uniprot | |
| S207 | Phosphorylation | Uniprot | |
| S209 | Phosphorylation | Uniprot | |
| S224 | Phosphorylation | Uniprot | |
| K232 | Methylation | Uniprot | |
| S254 | Phosphorylation | Uniprot | |
| T276 | Phosphorylation | Uniprot | |
| S278 | Phosphorylation | Uniprot | |
| S280 | Phosphorylation | Uniprot | |
| S282 | Phosphorylation | Uniprot | |
| S283 | Phosphorylation | Uniprot | |
| S286 | Phosphorylation | Uniprot | |
| T287 | Phosphorylation | Uniprot | |
| S293 | Phosphorylation | Uniprot | |
| S296 | Phosphorylation | Uniprot | |
| T305 | Phosphorylation | Uniprot | |
| Y306 | Phosphorylation | Uniprot | |
| S307 | Phosphorylation | Q15208 (STK38) | Uniprot |
| S332 | Phosphorylation | Uniprot | |
| S341 | Phosphorylation | Uniprot | |
| Y344 | Phosphorylation | Uniprot | |
| S356 | Phosphorylation | Uniprot | |
| S357 | Phosphorylation | Uniprot | |
| S359 | Phosphorylation | Uniprot | |
| S361 | Phosphorylation | Uniprot | |
| S364 | Phosphorylation | Uniprot | |
| S365 | Phosphorylation | Uniprot | |
| S367 | Phosphorylation | Uniprot | |
| S372 | Phosphorylation | Uniprot | |
| S373 | Phosphorylation | Uniprot | |
| S376 | Phosphorylation | Uniprot | |
| S391 | Phosphorylation | Uniprot | |
| S393 | Phosphorylation | Uniprot | |
| S395 | Phosphorylation | Uniprot | |
| S396 | Phosphorylation | Uniprot | |
| S397 | Phosphorylation | Uniprot | |
| S418 | Phosphorylation | Uniprot | |
| T438 | Phosphorylation | Uniprot | |
| S473 | Phosphorylation | Uniprot | |
| S481 | Phosphorylation | Uniprot | |
| S482 | Phosphorylation | Uniprot | |
| S494 | Phosphorylation | Uniprot | |
| S498 | Phosphorylation | Uniprot | |
| S499 | Phosphorylation | Uniprot | |
| S500 | Phosphorylation | Uniprot | |
| T519 | Phosphorylation | Uniprot | |
| S523 | Phosphorylation | Uniprot | |
| S538 | Phosphorylation | Uniprot | |
| S544 | Phosphorylation | Uniprot | |
| S547 | Phosphorylation | Uniprot | |
| S549 | Phosphorylation | Uniprot | |
| S553 | Phosphorylation | Uniprot | |
| K558 | Ubiquitination | Uniprot | |
| K560 | Ubiquitination | Uniprot | |
| S564 | Phosphorylation | Uniprot | |
| K583 | Ubiquitination | Uniprot | |
| K586 | Ubiquitination | Uniprot | |
| S588 | Phosphorylation | Uniprot | |
| S628 | Phosphorylation | Uniprot | |
| Y629 | Phosphorylation | Uniprot |
研究背景
Rab effector involved in protein trafficking from apical recycling endosomes to the apical plasma membrane. Involved in insulin granule exocytosis. May regulate V-ATPase intracellular transport in response to extracellular acidosis.
Phosphorylated on serine and threonine residues. Phosphorylation at Ser-357 is PKA-dependent.
Cytoplasm. Recycling endosome membrane>Peripheral membrane protein. Early endosome membrane>Peripheral membrane protein. Golgi apparatus membrane>Peripheral membrane protein. Cytoplasmic vesicle>Secretory vesicle membrane>Peripheral membrane protein. Mitochondrion membrane>Peripheral membrane protein.
Detected at low levels in heart, brain, placenta, lung, liver, adipocytes, kidney, spleen, skeletal muscle and pancreas.
Forms a heterooligomeric complex with RAB11FIP4. Binds NAPG and TROVE2. Binds RAB11A that has been activated by GTP binding.
Binds to vesicles enriched in neutral phospholipids via its C2 domain. The interaction is favored by Mg(2+) rather than Ca(2+).
研究领域
· Cellular Processes > Transport and catabolism > Endocytosis. (View pathway)
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