SEC61B Antibody - #DF9786

(4)  
产品: SEC61B 抗体
货号: DF9786
描述: Rabbit polyclonal antibody to SEC61B
应用: WB IHC IF/ICC
反应: Human, Mouse, Rat
预测: Pig, Bovine, Horse, Dog, Chicken
分子量: 10 kDa; 10kD(Calculated).
蛋白号: P60468
RRID: AB_2842981

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Pig(100%), Bovine(100%), Horse(100%), Dog(100%), Chicken(91%)
克隆:
Polyclonal
特异性:
SEC61B Antibody detects endogenous levels of total SEC61B.
RRID:
AB_2842981
引用格式: Affinity Biosciences Cat# DF9786, RRID:AB_2842981.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Protein translocation complex beta; Protein transport protein SEC61 beta subunit; Protein transport protein Sec61 subunit beta; SC61B_HUMAN; SEC 61B; SEC61 B; Sec61 beta subunit; Sec61 complex beta subunit; SEC61B;

抗原和靶标

免疫原:
Uniprot:

P60468(SC61B_HUMAN) >>Visit HPA database.

基因/基因ID:
SEC61B(10952)
序列:
MPGPTPSGTNVGSSGRSPSKAVAARAAGSTVRQRKNASCGTRSAGRTTSAGTGGMWRFYTEDSPGLKVGPVPVLVMSLLFIASVFMLHIWGKYTRS

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Dog
100
Chicken
91
Xenopus
75
Zebrafish
75
Sheep
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - P60468 作为底物

Site PTM Type Enzyme
M1 Acetylation
P2 Acetylation
T5 Phosphorylation
S7 Phosphorylation
T9 Phosphorylation
S13 Phosphorylation
S14 Phosphorylation
S17 Phosphorylation
S19 Phosphorylation
K20 Ubiquitination
S29 Phosphorylation
T30 Phosphorylation
S38 Phosphorylation
S43 Phosphorylation
S49 Phosphorylation
T52 Phosphorylation
T60 Phosphorylation
S63 Phosphorylation

研究背景

功能:

Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across endoplasmic reticulum (ER) (By similarity). Required for PKD1/Polycystin-1 biogenesis (By similarity).

细胞定位:

Endoplasmic reticulum membrane>Single-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
亚基结构:

The ER translocon complex consists of channel-forming core components SEC61A1, SEC61B and SEC61G and different auxiliary components such as SEC62 and SEC63.

蛋白家族:

Belongs to the SEC61-beta family.

研究领域

· Cellular Processes > Transport and catabolism > Phagosome.   (View pathway)

· Genetic Information Processing > Folding, sorting and degradation > Protein export.

· Genetic Information Processing > Folding, sorting and degradation > Protein processing in endoplasmic reticulum.   (View pathway)

· Human Diseases > Infectious diseases: Bacterial > Vibrio cholerae infection.

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