| 产品: | ESCO1 抗体 |
| 货号: | DF9657 |
| 描述: | Rabbit polyclonal antibody to ESCO1 |
| 应用: | WB IHC |
| 反应: | Human, Mouse |
| 预测: | Horse, Dog |
| 分子量: | 95 kDa; 95kD(Calculated). |
| 蛋白号: | Q5FWF5 |
| RRID: | AB_2842853 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF9657, RRID:AB_2842853.
展开/折叠
A930014I12Rik; CTF; CTF7 homolog 1; CTF7, S. cerevisiae, homolog of, 1; ECO1; ECO1 homolog 1; ECO1, S. cerevisiae, homolog of, 1; EFO1; EFO1p; ESCO1; ESCO1_HUMAN; ESO1; ESO1 homolog 1; ESO1, S. pombe, homolog of, 1; Establishment factor like protein 1; Establishment factor ortholog 1; Establishment factor-like protein 1; Establishment of cohesion 1 homolog 1; Establishment of cohesion 1, S. cerevisiae, homolog of; establishment of sister chromatid cohesion N-acetyltransferase 1; hEFO1; HGNC:24645; KIAA1911; N acetyltransferase ESCO1; N-acetyltransferase ESCO1;
抗原和靶标
Widely expressed. Expressed in heart, brain, liver, placenta, lung, kidney and pancreas. Highly expressed in muscle.
- Q5FWF5 ESCO1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MMSIQEKSKENSSKVTKKSDDKNSETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQPELETRMSTRSSKAASNDKATKSINKNTVTVRGYSQESTKKKLSQKKLVHENPKANEQLNRRSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSNKTSQKHVKRKVLEVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEKCPQKTTRRDETKPVPVTSEVKRSKMATSVVPKKNEMKKSVHTQVNTNTTLPKSPQPSVPEQSDNELEQAGKSKRGSILQLCEEIAGEIESDNVEVKKESSQMESVKEEKPTEIKLEETSVERQILHQKETNQDVQCNRFFPSRKTKPVKCILNGINSSAKKNSNWTKIKLSKFNSVQHNKLDSQVSPKLGLLRTSFSPPALEMHHPVTQSTFLGTKLHDRNITCQQEKMKEINSEEVKINDITVEINKTTERAPENCHLANEIKPSDPPLDNQMKHSFDSASNKNFSQCLESKLENSPVENVTAASTLLSQAKIDTGENKFPGSAPQQHSILSNQTSKSSDNRETPRNHSLPKCNSHLEITIPKDLKLKEAEKTDEKQLIIDAGQKRFGAVSCNVCGMLYTASNPEDETQHLLFHNQFISAVKYVGWKKERILAEYPDGRIIMVLPEDPKYALKKVDEIREMVDNDLGFQQAPLMCYSRTKTLLFISNDKKVVGCLIAEHIQWGYRVIEEKLPVIRSEEEKVRFERQKAWCCSTLPEPAICGISRIWVFSMMRRKKIASRMIECLRSNFIYGSYLSKEEIAFSDPTPDGKLFATQYCGTGQFLVYNFINGQNST
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
研究背景
Acetyltransferase required for the establishment of sister chromatid cohesion. Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during S phase. Acts by mediating the acetylation of cohesin component SMC3.
Phosphorylated during mitosis, when associated with chromosomes.
Nucleus. Chromosome.
Note: Nuclear at interphase, associated with chromosomes during mitosis.
Widely expressed. Expressed in heart, brain, liver, placenta, lung, kidney and pancreas. Highly expressed in muscle.
The subunit structure is controversial. Monomer. Homodimer.
The N-terminal region seems to be responsible for association with chromosomes, thus excluding any involvement of the Zn finger in this process.
Belongs to the acetyltransferase family. ECO subfamily.
限制条款
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