产品: IMMP2L 抗体
货号: DF9630
描述: Rabbit polyclonal antibody to IMMP2L
应用: WB IHC IF/ICC
反应: Human, Mouse, Rat
预测: Zebrafish, Bovine, Horse, Xenopus
分子量: 20 kDa; 20kD(Calculated).
蛋白号: Q96T52
RRID: AB_2842826

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:1000-3000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Zebrafish(91%), Bovine(100%), Horse(100%), Xenopus(100%)
克隆:
Polyclonal
特异性:
IMMP2L Antibody detects endogenous levels of total IMMP2L.
RRID:
AB_2842826
引用格式: Affinity Biosciences Cat# DF9630, RRID:AB_2842826.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

EC 3.4.21; IMP2; IMP2 inner mitochondrial membrane peptidase like (S. cerevisiae); IMP2 inner mitochondrial membrane protease like (S. cerevisiae); IMP2 inner mitochondrial membrane protease like; IMP2 like; IMP2 like protein; IMP2-LIKE; Inner mitochondrial membrane peptidase 2 like; Mitochondrial inner membrane protease subunit 2; OTTHUMP00000207168; OTTHUMP00000207189;

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
表达:
Q96T52 IMP2L_HUMAN:

Expressed in all tissues tested except adult liver and lung.

序列:
MAQSQGWVKRYIKAFCKGFFVAVPVAVTFLDRVACVARVEGASMQPSLNPGGSQSSDVVLLNHWKVRNFEVHRGDIVSLVSPKNPEQKIIKRVIALEGDIVRTIGHKNRYVKVPRGHIWVEGDHHGHSFDSNSFGPVSLGLLHAHATHILWPPERWQKLESVLPPERLPVQREEE

种属预测

种属预测:

score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。

Species
Results
Score
Horse
100
Bovine
100
Xenopus
100
Zebrafish
91
Pig
0
Sheep
0
Dog
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q96T52 作为底物

Site PTM Type Enzyme
S43 Phosphorylation
S47 Phosphorylation
K83 Ubiquitination
K88 Ubiquitination
K112 Methylation

研究背景

功能:

Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO.

细胞定位:

Mitochondrion inner membrane>Single-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Expressed in all tissues tested except adult liver and lung.

亚基结构:

Heterodimer of 2 subunits, IMMPL1 and IMMPL2.

蛋白家族:

Belongs to the peptidase S26 family. IMP2 subfamily.

研究领域

· Genetic Information Processing > Folding, sorting and degradation > Protein export.

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