| 产品: | C1QL3 抗体 |
| 货号: | DF9408 |
| 描述: | Rabbit polyclonal antibody to C1QL3 |
| 应用: | WB |
| 反应: | Human, Mouse |
| 预测: | Pig, Bovine, Rabbit, Chicken |
| 分子量: | 27 kDa; 27kD(Calculated). |
| 蛋白号: | Q5VWW1 |
| RRID: | AB_2842604 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF9408, RRID:AB_2842604.
展开/折叠
C1q and tumor necrosis factor-related protein 13; C1q/TNF-related protein 13; C1ql; C1QL3; C1QL3_HUMAN; C1QTNF13; Complement C1q-like protein 3; Complement component 1, q subcomponent-like 3; CTRP13; K100;
抗原和靶标
Highly expressed in adipose tissue, with expression levels at least 2 orders of magnitude higher than in other tissues, including brain and kidney.
- Q5VWW1 C1QL3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MVLLLVILIPVLVSSAGTSAHYEMLGTCRMVCDPYGGTKAPSTAATPDRGLMQSLPTFIQGPKGEAGRPGKAGPRGPPGEPGPPGPMGPPGEKGEPGRQGLPGPPGAPGLNAAGAISAATYSTVPKIAFYAGLKRQHEGYEVLKFDDVVTNLGNHYDPTTGKFTCSIPGIYFFTYHVLMRGGDGTSMWADLCKNNQVRASAIAQDADQNYDYASNSVVLHLEPGDEVYIKLDGGKAHGGNNNKYSTFSGFIIYAD
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
研究背景
May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity). Plays a role in glucose homeostasis. Via AMPK signaling pathway, stimulates glucose uptake in adipocytes, myotubes and hepatocytes and enhances insulin-stimulated glucose uptake. In a hepatoma cell line, reduces the expression of gluconeogenic enzymes G6PC and PCK1 and hence decreases de novo glucose production (By similarity).
Secreted.
Highly expressed in adipose tissue, with expression levels at least 2 orders of magnitude higher than in other tissues, including brain and kidney.
Forms homooligomers. Interacts with ADGRB3. Interacts with C1QL2 and C1QL4, when proteins are coexpressed; this interaction does not occur after secretion.
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