| 产品: | ACAP2 抗体 |
| 货号: | DF9359 |
| 描述: | Rabbit polyclonal antibody to ACAP2 |
| 应用: | WB IF/ICC |
| 反应: | Human, Mouse, Rat, Monkey |
| 预测: | Pig, Horse, Sheep, Rabbit, Chicken |
| 分子量: | 88 kDa; 88kD(Calculated). |
| 蛋白号: | Q15057 |
| RRID: | AB_2842555 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF9359, RRID:AB_2842555.
展开/折叠
ACAP 2; ACAP2; ACAP2_HUMAN; ANK repeat and PH domain-containing protein 2; Arf GAP with coiled coil ANK repeat and PH domain containing protein 2; Arf GAP with coiled coil ANK repeat and PH domains 2; Arf-GAP with coiled-coil; ArfGAP with coiled coil ankyrin repeat and PH domains 2; CENT B 2; Centaurin beta2; Centaurin-beta-2; CENTB 2; CENTB2; Cnt b2; Cnt-b2; Cntb2; KIAA0041; Similar to yeast ZINC FINGER PROTEIN GCS1;
抗原和靶标
- Q15057 ACAP2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MKMTVDFEECLKDSPRFRAALEEVEGDVAELELKLDKLVKLCIAMIDTGKAFCVANKQFMNGIRDLAQYSSNDAVVETSLTKFSDSLQEMINFHTILFDQTQRSIKAQLQNFVKEDLRKFKDAKKQFEKVSEEKENALVKNAQVQRNKQHEVEEATNILTATRKCFRHIALDYVLQINVLQSKRRSEILKSMLSFMYAHLAFFHQGYDLFSELGPYMKDLGAQLDRLVVDAAKEKREMEQKHSTIQQKDFSSDDSKLEYNVDAANGIVMEGYLFKRASNAFKTWNRRWFSIQNNQLVYQKKFKDNPTVVVEDLRLCTVKHCEDIERRFCFEVVSPTKSCMLQADSEKLRQAWIKAVQTSIATAYREKGDESEKLDKKSSPSTGSLDSGNESKEKLLKGESALQRVQCIPGNASCCDCGLADPRWASINLGITLCIECSGIHRSLGVHFSKVRSLTLDTWEPELLKLMCELGNDVINRVYEANVEKMGIKKPQPGQRQEKEAYIRAKYVERKFVDKYSISLSPPEQQKKFVSKSSEEKRLSISKFGPGDQVRASAQSSVRSNDSGIQQSSDDGRESLPSTVSANSLYEPEGERQDSSMFLDSKHLNPGLQLYRASYEKNLPKMAEALAHGADVNWANSEENKATPLIQAVLGGSLVTCEFLLQNGANVNQRDVQGRGPLHHATVLGHTGQVCLFLKRGANQHATDEEGKDPLSIAVEAANADIVTLLRLARMNEEMRESEGLYGQPGDETYQDIFRDFSQMASNNPEKLNRFQQDSQKF
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q15057 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K57 | Ubiquitination | Uniprot | |
| K106 | Ubiquitination | Uniprot | |
| K114 | Ubiquitination | Uniprot | |
| K134 | Ubiquitination | Uniprot | |
| K140 | Ubiquitination | Uniprot | |
| K148 | Ubiquitination | Uniprot | |
| Y197 | Phosphorylation | Uniprot | |
| K233 | Ubiquitination | Uniprot | |
| K248 | Ubiquitination | Uniprot | |
| Y259 | Phosphorylation | Uniprot | |
| Y272 | Phosphorylation | Uniprot | |
| S278 | Phosphorylation | Uniprot | |
| Y298 | Phosphorylation | Uniprot | |
| K319 | Ubiquitination | Uniprot | |
| S334 | Phosphorylation | Uniprot | |
| K347 | Ubiquitination | Uniprot | |
| T358 | Phosphorylation | Uniprot | |
| K367 | Acetylation | Uniprot | |
| K377 | Ubiquitination | Uniprot | |
| S378 | Phosphorylation | Uniprot | |
| S379 | Phosphorylation | Uniprot | |
| S381 | Phosphorylation | Uniprot | |
| T382 | Phosphorylation | Uniprot | |
| S384 | Phosphorylation | Uniprot | |
| S387 | Phosphorylation | Uniprot | |
| K450 | Ubiquitination | Uniprot | |
| K515 | Acetylation | Uniprot | |
| S517 | Phosphorylation | Uniprot | |
| S519 | Phosphorylation | Uniprot | |
| S521 | Phosphorylation | Uniprot | |
| K527 | Acetylation | Uniprot | |
| K532 | Acetylation | Uniprot | |
| S540 | Phosphorylation | Uniprot | |
| S563 | Phosphorylation | Uniprot | |
| S581 | Phosphorylation | Uniprot | |
| S584 | Phosphorylation | Uniprot | |
| Y586 | Phosphorylation | Uniprot | |
| S595 | Phosphorylation | Uniprot | |
| S596 | Phosphorylation | Uniprot | |
| K602 | Ubiquitination | Uniprot | |
| K617 | Acetylation | Uniprot | |
| K695 | Acetylation | Uniprot | |
| K708 | Ubiquitination | Uniprot | |
| S738 | Phosphorylation | Uniprot | |
| Y742 | Phosphorylation | Uniprot | |
| T749 | Phosphorylation | Uniprot | |
| Y750 | Phosphorylation | Uniprot | |
| K767 | Ubiquitination | Uniprot | |
| S775 | Phosphorylation | Uniprot |
研究背景
GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6).
Endosome membrane>Peripheral membrane protein.
Widely expressed. Highest level in lung.
Interacts with RAB35 (GTP-bound form); the interaction is direct and probably recruits ACAP2 to membranes. Interacts with MICALL1; the interaction is indirect through RAB35 (By similarity).
研究领域
· Cellular Processes > Transport and catabolism > Endocytosis. (View pathway)
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