AXIN1 Antibody - #DF9264

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产品: AXIN1 抗体
货号: DF9264
描述: Rabbit polyclonal antibody to AXIN1
应用: WB IHC
文献验证: WB
反应: Human, Mouse, Rat
预测: Pig, Zebrafish, Bovine, Horse, Dog, Chicken, Xenopus
蛋白号: O15169
RRID: AB_2842460

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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WB Handbook
IHC Protocol
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产品描述

来源:
Rabbit
应用:
IHC 1:50-1:200, WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
AXIN1 Antibody detects endogenous levels of total AXIN1.
RRID:
AB_2842460
引用格式: Affinity Biosciences Cat# DF9264, RRID:AB_2842460.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

AI316800; AXIN; Axin 1; Axin-1; axin1; AXIN1_HUMAN; Axis inhibition protein 1; Axis Inhibitor 1; Fu; fused; Fused, mouse, homolog of; hAxin; Kb; Ki; kinky; knobbly; MGC132911; MGC52315; PPP1R49; Protein Fused; Protein phosphatase 1 regulatory subunit 49;

抗原和靶标

免疫原:

A synthesized peptide derived from human AXIN1, corresponding to a region within C-terminal amino acids.

基因/基因ID:
AXIN1(8312)

研究领域

· Cellular Processes > Cellular community - eukaryotes > Signaling pathways regulating pluripotency of stem cells.   (View pathway)

· Environmental Information Processing > Signal transduction > Wnt signaling pathway.   (View pathway)

· Environmental Information Processing > Signal transduction > Hippo signaling pathway.   (View pathway)

· Human Diseases > Infectious diseases: Viral > Human papillomavirus infection.

· Human Diseases > Cancers: Overview > Pathways in cancer.   (View pathway)

· Human Diseases > Cancers: Specific types > Colorectal cancer.   (View pathway)

· Human Diseases > Cancers: Specific types > Endometrial cancer.   (View pathway)

· Human Diseases > Cancers: Specific types > Basal cell carcinoma.   (View pathway)

· Human Diseases > Cancers: Specific types > Breast cancer.   (View pathway)

· Human Diseases > Cancers: Specific types > Hepatocellular carcinoma.   (View pathway)

· Human Diseases > Cancers: Specific types > Gastric cancer.   (View pathway)

文献引用

1). Pygo2 Regulates Adiposity and Glucose Homeostasis via β-Catenin-Axin2-GSK3β Signaling Pathway. DIABETES, 2018 (PubMed: 30279163) [IF=6.2]

Application: WB    Species: mouse    Sample:

Supplemental Figure 2.| Simultaneous overexpression of Axin1 also significantly compromised the Pygo2 knockout-induced C/EBPβ and Snail function changes. The expression of Pygo2 was knocked out by CRISPR/CAS9 technique with or without lentivirus overexpression of Axin1 to the level that could compensate the reduction of Axin2. (A) The phosphorylated C/EBPβ and Snail protein expression were detected by western blotting. (B) The C/EBPβ occupancy on the PPARγ promoter was assessed by ChIP assay. For B, each bar represents the average value of three independent experiments and error bars represent SD. *P <0.05, **P < 0.01.
2). The truncated AXIN1 isoform promotes hepatocellular carcinoma metastasis through SRSF9-mediated exon 9 skipping. Molecular and cellular biochemistry, 2025 (PubMed: 38748384) [IF=3.5]
3). PITX2 functions as a transcription factor for GPX4 and protects pancreatic cancer cells from ferroptosis. Experimental cell research, 2024 (PubMed: 38710403) [IF=3.3]
4). Cannabidiol inhibits invasion and metastasis in colorectal cancer cells by reversing epithelial–mesenchymal transition through the Wnt/β-catenin signaling pathway. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2023 (PubMed: 35960375) [IF=2.7]
5). Cannabidiol inhibits invasion and metastasis in colorectal cancer cells by reversing epithelial-mesenchymal transition through the Wnt/β-catenin signaling pathway. Journal of cancer research and clinical oncology, 2023 (PubMed: 35960375) [IF=2.7]

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