ALDH1A3 Antibody - #DF9187

>>买3送1 已结束>>
(3)  
产品: ALDH1A3 抗体
货号: DF9187
描述: Rabbit polyclonal antibody to ALDH1A3
应用: WB IHC
反应: Human, Mouse, Rat
预测: Pig, Bovine, Horse, Sheep, Rabbit
分子量: 56 kDa; 56kD(Calculated).
蛋白号: P47895
RRID: AB_2842383

浏览相似产品>>

   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

联系销售
相关下载
MS Report
HPLC Report
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Pig(89%), Bovine(89%), Horse(89%), Sheep(89%), Rabbit(100%)
克隆:
Polyclonal
特异性:
ALDH1A3 Antibody detects endogenous levels of total ALDH1A3.
RRID:
AB_2842383
引用格式: Affinity Biosciences Cat# DF9187, RRID:AB_2842383.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Acetaldehyde dehydrogenase 6; AL1A3_HUMAN; Aldehyde dehydrogenase 1A3; Aldehyde dehydrogenase 6; Aldehyde dehydrogenase family 1 member A3; Aldh1a3; ALDH1A6; ALDH6; RALDH 3; Retinaldehyde dehydrogenase 3; V1;

抗原和靶标

免疫原:
Uniprot:

P47895(AL1A3_HUMAN) >>Visit HPA database.

基因/基因ID:
ALDH1A3(220)
表达:
P47895 AL1A3_HUMAN:

Expressed at low levels in many tissues and at higher levels in salivary gland, stomach, and kidney.

序列:
MATANGAVENGQPDRKPPALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLGDKNP

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Rabbit
100
Pig
89
Horse
89
Bovine
89
Sheep
89
Dog
78
Xenopus
67
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - P47895 作为底物

Site PTM Type Enzyme
A2 Acetylation
K30 Ubiquitination
K33 Ubiquitination
K44 Ubiquitination
T56 Phosphorylation
K150 Ubiquitination
K154 Ubiquitination
K252 Ubiquitination
K263 Ubiquitination
K266 Ubiquitination
T278 Phosphorylation
Y327 Phosphorylation
S328 Phosphorylation
K340 Ubiquitination
K350 Ubiquitination
K360 Ubiquitination
K364 Ubiquitination
K373 Ubiquitination
K394 Ubiquitination
K409 Ubiquitination
K421 Ubiquitination
K423 Ubiquitination
S424 Phosphorylation
K430 Ubiquitination
Y437 Phosphorylation
T440 Phosphorylation
K446 Ubiquitination
Y492 Phosphorylation
Y497 Phosphorylation
T498 Phosphorylation

研究背景

功能:

NAD-dependent aldehyde dehydrogenase that catalyzes the formation of retinoic acid. Has high activity with all-trans retinal, and has much lower in vitro activity with acetaldehyde. Required for the biosynthesis of normal levels of retinoic acid in the embryonic ocular and nasal regions; retinoic acid is required for normal embryonic development of the eye and the nasal region (By similarity).

细胞定位:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Expressed at low levels in many tissues and at higher levels in salivary gland, stomach, and kidney.

亚基结构:

Homotetramer.

蛋白家族:

Belongs to the aldehyde dehydrogenase family.

研究领域

· Human Diseases > Cancers: Overview > Chemical carcinogenesis.

· Metabolism > Carbohydrate metabolism > Glycolysis / Gluconeogenesis.

· Metabolism > Amino acid metabolism > Histidine metabolism.

· Metabolism > Amino acid metabolism > Tyrosine metabolism.

· Metabolism > Amino acid metabolism > Phenylalanine metabolism.

· Metabolism > Metabolism of other amino acids > beta-Alanine metabolism.

· Metabolism > Xenobiotics biodegradation and metabolism > Metabolism of xenobiotics by cytochrome P450.

· Metabolism > Xenobiotics biodegradation and metabolism > Drug metabolism - cytochrome P450.

· Metabolism > Global and overview maps > Metabolic pathways.

限制条款

产品的规格、报价、验证数据请以官网为准，官网链接：www.affbiotech.com | www.affbiotech.cn（简体中文）| www.affbiotech.jp（日本語）

产品的数据信息为Affinity所有，未经授权不得收集Affinity官网数据或资料用于商业用途，对抄袭产品数据的行为我们将保留诉诸法律的权利。

产品相关数据会因产品批次、产品检测情况随时调整，如您已订购该产品，请以订购时随货说明书为准，否则请以官网内容为准，官网内容有改动时恕不另行通知。

Affinity保证所销售产品均经过严格质量检测。如您购买的商品在规定时间内出现问题需要售后时，请您在Affinity官方渠道提交售后申请。

产品仅供科学研究使用。不用于诊断和治疗。 

产品未经授权不得转售。

Affinity Biosciences将不会对在使用我们的产品时可能发生的专利侵权或其他侵权行为负责。Affinity Biosciences, Affinity Biosciences标志和所有其他商标所有权归Affinity Biosciences LTD.