LYPLA2 Antibody - #DF9160

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产品: LYPLA2 抗体
货号: DF9160
描述: Rabbit polyclonal antibody to LYPLA2
应用: WB
反应: Human, Mouse, Rat
预测: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken
分子量: 25 kDa; 25kD(Calculated).
蛋白号: O95372
RRID: AB_2842356

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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MS Report
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MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(80%)
克隆:
Polyclonal
特异性:
LYPLA2 Antibody detects endogenous levels of total LYPLA2.
RRID:
AB_2842356
引用格式: Affinity Biosciences Cat# DF9160, RRID:AB_2842356.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Acyl protein thioesterase 2; Acyl protein thioesterase; Acyl-protein thioesterase 2; APT 2; APT-2; APT2; DJ886K2.4; EC 3.1.2.-; LPL I; LPL II; LPL-II; LYPA2_HUMAN; LYPLA 2; Lypla2; Lysophospholipase II; LysoPLA II; OTTHUMP00000002999; OTTHUMP00000044831;

抗原和靶标

免疫原:
Uniprot:

O95372(LYPA2_HUMAN) >>Visit HPA database.

基因/基因ID:
LYPLA2(11313)
序列:
MCGNTMSVPLLTDAATVSGAERETAAVIFLHGLGDTGHSWADALSTIRLPHVKYICPHAPRIPVTLNMKMVMPSWFDLMGLSPDAPEDEAGIKKAAENIKALIEHEMKNGIPANRIVLGGFSQGGALSLYTALTCPHPLAGIVALSCWLPLHRAFPQAANGSAKDLAILQCHGELDPMVPVRFGALTAEKLRSVVTPARVQFKTYPGVMHSSCPQEMAAVKEFLEKLLPPV

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Rabbit
100
Chicken
80
Xenopus
70
Zebrafish
70
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - O95372 作为底物

Site PTM Type Enzyme
S39 Phosphorylation
K53 Ubiquitination
C56 S-Nitrosylation
K100 Ubiquitination
K108 Ubiquitination
K164 Ubiquitination
K190 Acetylation
K190 Ubiquitination
K203 Ubiquitination
K221 Ubiquitination
K226 Ubiquitination

研究背景

功能:

Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins, GAP43, ZDHHC6 or HRAS. Deacylates GAP43. Mediates depalmitoylation of ZDHHC6. Has lysophospholipase activity (By similarity).

细胞定位:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
蛋白家族:

Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

研究领域

· Metabolism > Lipid metabolism > Glycerophospholipid metabolism.

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