产品: ABLIM1 抗体
货号: DF9145
描述: Rabbit polyclonal antibody to ABLIM1
应用: WB IHC IF/ICC
反应: Human, Mouse
分子量: 88 kDa; 88kD(Calculated).
蛋白号: O14639
RRID: AB_2842341

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:1000-3000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse
克隆:
Polyclonal
特异性:
ABLIM1 Antibody detects endogenous levels of total ABLIM1.
RRID:
AB_2842341
引用格式: Affinity Biosciences Cat# DF9145, RRID:AB_2842341.
偶联:
Unconjugated. 130
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

ABLIM 1; ABLIM; abLIM-1; ABLIM-L; ABLIM-M; ABLIM-S; ABLIM1; ABLM1_HUMAN; Actin binding double zinc finger protein; Actin binding LIM protein 1; Actin binding LIM protein family member 1; Actin-binding double zinc finger protein; Actin-binding LIM protein 1; Actin-binding LIM protein family member 1; DKFZp781D0148; FLJ14564; KIAA0059; LIM actin binding protein 1; LIMAB 1; LIMAB1; Limatin; MGC1224; MGC125264; OTTHUMP00000020530; OTTHUMP00000020531; OTTHUMP00000020532; OTTHUMP00000020533; OTTHUMP00000020534; OTTHUMP00000020535; OTTHUMP00000020536; OTTHUMP00000020537; RGD1565768; RP11-317F20.1;

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
表达:
O14639 ABLM1_HUMAN:

Detected in liver, heart, skeletal muscle, brain and retina, where it is concentrated in the inner segment and in the outer plexiform layers.

序列:
MPAFLGLKCLGKLCSSEKSKVTSSERTSARGSNRKRLIVEDRRVSGTSFTAHRRATITHLLYLCPKDYCPRGRVCNSVDPFVAHPQDPHHPSEKPVIHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRPTRTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSGYDDKQERQSLGESPRTLSPTPSAEGYQDVRDRMIHRSTSQGSINSPVYSRHSYTPTTSRSPQHFHRPGNEPSSGRNSPLPYRPDSRPLTPTYAQAPKHFHVPDQGINIYRKPPIYKQHAALAAQSKSSEDIIKFSKFPAAQAPDPSETPKIETDHWPGPPSFAVVGPDMKRRSSGREEDDEELLRRRQLQEEQLMKLNSGLGQLILKEEMEKESRERSSLLASRYDSPINSASHIPSSKTASLPGYGRNGLHRPVSTDFAQYNSYGDVSGGVRDYQTLPDGHMPAMRMDRGVSMPNMLEPKIFPYEMLMVTNRGRNKILREVDRTRLERHLAPEVFREIFGMSIQEFDRLPLWRRNDMKKKAKLF

翻译修饰 - O14639 作为底物

Site PTM Type Enzyme
T22 Phosphorylation
S28 Phosphorylation
K121 Ubiquitination
S215 Phosphorylation
S216 Phosphorylation
K234 Ubiquitination
K275 Ubiquitination
K345 Ubiquitination
T349 Phosphorylation
T351 Phosphorylation
S352 Phosphorylation
S353 Phosphorylation
S355 Phosphorylation
Y357 Phosphorylation
S358 Phosphorylation
S362 Phosphorylation
S363 Phosphorylation
S367 Phosphorylation
T371 Phosphorylation
Y373 Phosphorylation
Y383 Phosphorylation
K384 Ubiquitination
K393 Ubiquitination
Y396 Phosphorylation
T405 Phosphorylation
Y406 Phosphorylation
Y410 Phosphorylation
T411 Phosphorylation
S412 Phosphorylation
Y414 Phosphorylation
K417 Ubiquitination
S422 Phosphorylation
S426 Phosphorylation
T429 Phosphorylation
S431 Phosphorylation
T433 Phosphorylation
S435 Phosphorylation
Y439 Phosphorylation
S450 Phosphorylation
T451 Phosphorylation
S452 O-Glycosylation
S452 Phosphorylation
S455 Phosphorylation
S458 Phosphorylation
Y461 Phosphorylation
S462 Phosphorylation
S465 Phosphorylation
Y466 Phosphorylation
T467 Phosphorylation
T469 Phosphorylation
T502 Phosphorylation
Y505 Phosphorylation
Y522 Phosphorylation
Y528 Phosphorylation
K529 Methylation
K529 Ubiquitination
S538 Phosphorylation
S540 Phosphorylation
S541 Phosphorylation
K546 Ubiquitination
K549 Ubiquitination
S586 Phosphorylation
S587 Phosphorylation
S631 Phosphorylation
S632 Phosphorylation
S636 Phosphorylation
Y638 Phosphorylation
S640 Phosphorylation
S644 Phosphorylation
S646 Phosphorylation
S651 Phosphorylation
K652 Ubiquitination
S655 Phosphorylation
Y659 Phosphorylation
S669 Phosphorylation
T670 Phosphorylation
Y675 Phosphorylation
S677 Phosphorylation
Y678 Phosphorylation
Y688 Phosphorylation
T690 Phosphorylation
S706 Phosphorylation
Y718 Phosphorylation
T724 Phosphorylation
R726 Methylation

研究背景

功能:

May act as scaffold protein (By similarity). May play a role in the development of the retina. Has been suggested to play a role in axon guidance.

细胞定位:

Cytoplasm. Cytoplasm>Cytoskeleton.
Note: Associated with the cytoskeleton.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Detected in liver, heart, skeletal muscle, brain and retina, where it is concentrated in the inner segment and in the outer plexiform layers.

亚基结构:

Binds F-actin. Interacts with ABRA.

研究领域

· Organismal Systems > Development > Axon guidance.   (View pathway)

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