LAMC2 Antibody - #DF9052

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产品: LAMC2 抗体
货号: DF9052
描述: Rabbit polyclonal antibody to LAMC2
应用: WB IF/ICC
文献验证: WB
反应: Human
预测: Pig, Bovine, Horse, Dog, Xenopus
蛋白号: Q13753
RRID: AB_2842248

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:1000-3000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
克隆:
Polyclonal
特异性:
LAMC2 Antibody detects endogenous levels of total LAMC2.
RRID:
AB_2842248
引用格式: Affinity Biosciences Cat# DF9052, RRID:AB_2842248.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

3918; B2T; BM600; Cell-scattering factor 140 kDa subunit; CSF 140 kDa subunit; CSF; EBR2; EBR2A; Epiligrin subunit gamma; Kalinin subunit gamma; Kalinin/nicein/epiligrin 100 kDa subunit; Ladsin 140 kDa subunit; LAMB2T; LAMC2; LAMC2_HUMAN; Laminin 5 gamma 2 subunit; Laminin B2t chain; Laminin gamma 2; laminin gamma 2 chain; Laminin subunit gamma-2; Laminin-5 subunit gamma; LAMNB2; Large adhesive scatter factor 140 kDa subunit; MGC138491; MGC141938; Nicein subunit gamma; NICEIN-100KDA;

抗原和靶标

免疫原:

A synthesized peptide derived from human LAMC2, corresponding to a region within the internal amino acids.

基因/基因ID:
LAMC2(3918)

研究领域

· Cellular Processes > Cellular community - eukaryotes > Focal adhesion.   (View pathway)

· Environmental Information Processing > Signal transduction > PI3K-Akt signaling pathway.   (View pathway)

· Environmental Information Processing > Signaling molecules and interaction > ECM-receptor interaction.   (View pathway)

· Human Diseases > Infectious diseases: Parasitic > Toxoplasmosis.

· Human Diseases > Infectious diseases: Parasitic > Amoebiasis.

· Human Diseases > Infectious diseases: Viral > Human papillomavirus infection.

· Human Diseases > Cancers: Overview > Pathways in cancer.   (View pathway)

· Human Diseases > Cancers: Specific types > Small cell lung cancer.   (View pathway)

文献引用

1). Overexpression of Laminin 5γ2 Chain Correlates with Tumor Cell Proliferation, Invasion, and Poor Prognosis in Laryngeal Squamous Cell Carcinoma. Journal of Oncology, 2022 (PubMed: 36284634)

Application: WB    Species: Human    Sample: LSCC cells

Figure 2 LAMC2 was highly expressed in LSCC cells. (a) and (b): LAMC2 mRNA and protein expression in LSCC cells texted by qRT-PCR and western blot. (c) and (d): qRT-PCR and western blot were performed to detect the effect of LAMC2 overexpression on LAMC2 mRNA and protein expression. (e) and (f): LAMC2 knockdown inhibited the expression of LAMC2 mRNA and protein in AMC-HN-8 cells. qRT-PCR and Western blot were performed to detected the effect of LAMC2 knockdown on LAMC2 mRNA and protein expression. Data were expressed as mean ± SD, n = 3. Compared to the 16HBE group, ▲▲P < 0.01. Compared to the vector group, ##P < 0.01. Compared to the shNC group, ∗∗P < 0.01.

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