Cytochrome P450 27C1 Antibody - #DF8922

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产品: Cytochrome P450 27C1 抗体
货号: DF8922
描述: Rabbit polyclonal antibody to Cytochrome P450 27C1
应用: WB IHC IF/ICC
反应: Human, Mouse, Rat
预测: Bovine, Horse, Dog
分子量: 43 kDa; 43kD(Calculated).
蛋白号: Q4G0S4
RRID: AB_2842118

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MS Report
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实验方案
WB Handbook
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产品描述

来源:
Rabbit
应用:
WB 1:1000-3000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
预测:
Bovine(89%), Horse(%), Dog(%)
克隆:
Polyclonal
特异性:
Cytochrome P450 27C1 Antibody detects endogenous levels of total Cytochrome P450 27C1.
RRID:
AB_2842118
引用格式: Affinity Biosciences Cat# DF8922, RRID:AB_2842118.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

C27C1_HUMAN; CYP27C1; Cytochrome P450 27C1; Cytochrome P450 family 27 subfamily C polypeptide 1; Cytochrome P450 family 27 subfamily C polypeptide 13; FLJ16008;

抗原和靶标

免疫原:
Uniprot:

Q4G0S4(C27C1_HUMAN) >>Visit HPA database.

基因/基因ID:
CYP27C1(339761)
表达:
Q4G0S4 C27C1_HUMAN:

Widely expressed, with highest levels in the liver, kidney and pancreas.

序列:
MRSVLRQRILKPKDVAIYSGEVNQVIADLIKRIYLLRSQAEDGETVTNVNDLFFKYSMEGVATILYESRLGCLENSIPQLTVEYIEALELMFSMFKTSMYAGAIPRWLRPFIPKPWREFCRSWDGLFKFSQIHVDNKLRDIQYQMDRGRRVSGGLLTYLFLSQALTLQEIYANVTEMLLAGVDTTSFTLSWTVYLLARHPEVQQTVYREIVKNLGERHVPTAADVPKVPLVRALLKETLRLFPVLPGNGRVTQEDLVIGGYLIPKGTQLALCHYATSYQDENFPRAKEFRPERWLRKGDLDRVDNFGSIPFGHGVRSCIGRRIAELEIHLVVIQLLQHFEIKTSSQTNAVHAKTHGLLTPGGPIHVRFVNRK

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Horse
100
Bovine
89
Dog
89
Sheep
78
Chicken
78
Pig
67
Xenopus
0
Zebrafish
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

研究背景

功能:

Catalyzes the conversion of all-trans retinol (also called vitamin A1, the precursor of 11-cis retinal) to 3,4-didehydroretinol (also called vitamin A2, the precursor of 11-cis 3,4-didehydroretinal). Also acts on all-trans retinal and all-trans retinoic acid.

细胞定位:

Membrane.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Widely expressed, with highest levels in the liver, kidney and pancreas.

蛋白家族:

Belongs to the cytochrome P450 family.

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