产品: RELT 抗体
货号: DF8712
描述: Rabbit polyclonal antibody to RELT
应用: WB IHC IF/ICC
文献验证: WB
反应: Human, Mouse
预测: Rat, Bovine, Sheep, Rabbit, Dog
蛋白ID: Q969Z4
RRID: AB_2841916

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
IHC 1:50-1:200, WB 1:1000-3000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse
克隆:
Polyclonal
特异性:
RELT Antibody detects endogenous levels of total RELT.
RRID:
AB_2841916
引用格式: Affinity Biosciences Cat# DF8712, RRID:AB_2841916.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Receptor expressed in lymphoid tissues; Relt; TNFRSF19L; TR19L_HUMAN; Tumor necrosis factor receptor superfamily member 19L;

抗原和靶标

免疫原:

A synthesized peptide derived from human RELT, corresponding to a region within C-terminal amino acids.

基因/基因ID:

研究领域

· Environmental Information Processing > Signaling molecules and interaction > Cytokine-cytokine receptor interaction.   (View pathway)

文献引用

1). Immune-related RELT drives clear cell renal cell carcinoma progression through JAK/STAT signaling pathway activation. Frontiers in immunology, 2025 (PubMed: 41376629) [IF=5.7]

Application: WB    Species: human    Sample: ccRCCtissues

FIGURE 1High expression ofRELTin ccRCC predicts poor prognosis (A) Increased or decreased RELT in diferent tumor types from The Cancer GenomeAtlas (TCGA) database were identifed by Tumor lmmunity Estimation Resource (TIMER): (B) Analysis of ccRCC samples from the TCGA database.With RELTlocated in the high-expression group; (C) The GEO database of the GSE53757 datasetRELT was highly expressed in the tumor group;(D) mRNA expression levelts of RELT in 541 ccRCC samples in the TCGA database were higher than in 72 normal samples: (E) TCGA database RELTexpression levels were high in ccRCC tissues matched to 72 normal tissues: (F-J) box plots of RELT expresstion versus TNM staging(F-H. pathological grading (l. and clinical staging ) in ccRCC samples from the TCGA database: ( diagnostic subject operating characteristicROC) curves of RELT in ccRCC: () Kaplan- Meier of RELT expression versus overallsurival: (M) RELT expression in ccRCC tissues is higher than thatin paracancerous tissues; (N) RELTexpression in ccRCC cell lines; (O) RELTimmunohistochemistry experiments of tumors and normal tissues inDatients with ccRCC: (P) Paired IRS scores for IHC resuits () Application of componentimaging heatmap to visualize the relationship between clinical information and high and low RELT expression in 59 patients; *P

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