RASSF4 Antibody - #DF8711

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产品: RASSF4 抗体
货号: DF8711
描述: Rabbit polyclonal antibody to RASSF4
应用: WB IF/ICC
反应: Human, Rat
预测: Pig, Bovine, Horse, Sheep, Rabbit, Dog
分子量: 36 kDa; 37kD(Calculated).
蛋白号: Q9H2L5
RRID: AB_2841915

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
WB 1:1000-3000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Rat
预测:
Pig(100%), Bovine(90%), Horse(80%), Sheep(100%), Rabbit(90%), Dog(100%)
克隆:
Polyclonal
特异性:
RASSF4 Antibody detects endogenous levels of total RASSF4.
RRID:
AB_2841915
引用格式: Affinity Biosciences Cat# DF8711, RRID:AB_2841915.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

3830411C14Rik; AD037; AI586137; MGC105606; MGC44914; OTTHUMP00000019493; Ras association (RalGDS/AF 6) domain family 4; Ras association (RalGDS/AF 6) domain family member 4; Ras association domain containing protein 4; Ras association domain family 4; Ras association domain-containing protein 4; RASF4_HUMAN; RASSF 4; Rassf4; RP11-285G1.4; Tumor suppressor RASSF4;

抗原和靶标

免疫原:
Uniprot:

Q9H2L5(RASF4_HUMAN) >>Visit HPA database.

基因/基因ID:
RASSF4(83937)
表达:
Q9H2L5 RASF4_HUMAN:

Widely expressed. Frequently down-regulated in tumor cell lines.

序列:
MKEDCLPSSHVPISDSKSIQKSELLGLLKTYNCYHEGKSFQLRHREEEGTLIIEGLLNIAWGLRRPIRLQMQDDREQVHLPSTSWMPRRPSCPLKEPSPQNGNITAQGPSIQPVHKAESSTDSSGPLEEAEEAPQLMRTKSDASCMSQRRPKCRAPGEAQRIRRHRFSINGHFYNHKTSVFTPAYGSVTNVRVNSTMTTLQVLTLLLNKFRVEDGPSEFALYIVHESGERTKLKDCEYPLISRILHGPCEKIARIFLMEADLGVEVPHEVAQYIKFEMPVLDSFVEKLKEEEEREIIKLTMKFQALRLTMLQRLEQLVEAK

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Pig
100
Sheep
100
Dog
100
Bovine
90
Rabbit
90
Horse
80
Zebrafish
57
Xenopus
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q9H2L5 作为底物

Site PTM Type Enzyme
K21 Ubiquitination
S91 Phosphorylation
S141 Phosphorylation
S168 Phosphorylation
K232 Methylation
S283 Phosphorylation

研究背景

功能:

Potential tumor suppressor. May act as a KRAS effector protein. May promote apoptosis and cell cycle arrest.

组织特异性:

Widely expressed. Frequently down-regulated in tumor cell lines.

亚基结构:

Interacts directly with activated KRAS in a GTP-dependent manner.

研究领域

· Environmental Information Processing > Signal transduction > Hippo signaling pathway - multiple species.   (View pathway)

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