Podocin Antibody - #DF8593

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产品: Podocin 抗体
货号: DF8593
描述: Rabbit polyclonal antibody to Podocin
应用: WB
文献验证: WB
反应: Human
预测: Mouse, Pig, Bovine, Horse, Sheep, Rabbit, Dog
蛋白号: Q9NP85
RRID: AB_2841797

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
克隆:
Polyclonal
特异性:
Podocin Antibody detects endogenous levels of total Podocin.
RRID:
AB_2841797
引用格式: Affinity Biosciences Cat# DF8593, RRID:AB_2841797.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Nephrosis 2, idiopathic, steroid resistant (podocin); nephrosis 2, idiopathic, steroid resistant; NPHS2; NPHS2 gene; PDCN; PODO_HUMAN; Podocin; SRN1;

抗原和靶标

免疫原:

A synthesized peptide derived from human Podocin, corresponding to a region within C-terminal amino acids.

基因/基因ID:
NPHS2(7827)

文献引用

1). CCDC92 deficiency ameliorates podocyte lipotoxicity in diabetic kidney disease. Metabolism: clinical and experimental, 2024 (PubMed: 37952690) [IF=10.8]

Application: WB    Species: Mouse    Sample:

Fig3f
2). Targeted inhibition of CX3CL1 limits podocytes ferroptosis to ameliorate cisplatin-induced acute kidney injury. Molecular medicine (Cambridge, Mass.), 2023 (PubMed: 37875838) [IF=6.0]

Application: WB    Species: Mouse    Sample: kidney tissues

Fig. 1 CX3CL1 deficiency alleviated kidney function damage in cisplatin-induced model mice. WT mice and CX3CL1-KO mice received cisplatin injections at 48 h. A Examination of the kidney’s histology using representative images of H&E and PAS staining. B The serum levels of BUN and Scr were evaluated in all mice groups. C Western blotting was conducted to determine the relative expression patterns of podocin, CX3CL1, nephrin, and WT1. D Representative images of podocyte ultrastructure in kidney tissues following cisplatin injection, as shown in TEM. Scale bar = 500 nm. E Representative micrographs of CX3CL1 and nephrin staining in kidney tissues. Scale bar = 10 μm. (WT, wild type; KO, knockdown; H&E, hematoxylin and eosin; PAS, periodic acid-Schiff; BUN, blood urea nitrogen; Scr, serum creatinine; WT1, Wilms tumor protein; TEM, transmission electron microscopy; p value was calculated by one-way analysis of variance and Tukey’s test.
3). Phloretin ameliorates diabetic nephropathy by inhibiting nephrin and podocin reduction through a non-hypoglycemic effect. Food & Function, 2022 (PubMed: 35622066) [IF=5.1]
4). CLEC14A protects against podocyte injury in mice with adriamycin nephropathy. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2021 (PubMed: 34107098) [IF=4.4]
5). Melittin induces autophagy to alleviate chronic renal failure in 5/6-nephrectomized rats and angiotensin II-induced damage in podocytes. Nutrition research and practice, 2024 (PubMed: 38584815) [IF=2.0]
6). The Yi-Qi-Bu-Shen recipe attenuates high glucose-induced podocyte injury via the inhibition of IKK-IκBα-NFκB and ERK/P38 MAPK signaling . International Journal of Clinical and Experimental Medicine, 2022 [IF=0.2]

Application: WB    Species: Human    Sample: podocytes

Figure 2. Effect of YB on HG-induced expression of nephrin, podocin and CD2AP in podocytes. A-C. Podocytes were treated with HG and YB for 24 hours and then mRNA levels of nephrin, podocin and CD2AP were determined by qRT-PCR. (*P

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