CD42b Antibody - #DF8519

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产品: CD42b 抗体
货号: DF8519
描述: Rabbit polyclonal antibody to CD42b
应用: WB IHC
文献验证: WB
反应: Human, Mouse
预测: Bovine, Rabbit, Dog
蛋白号: P07359
RRID: AB_2841724

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse
克隆:
Polyclonal
特异性:
CD42b Antibody detects endogenous levels of total CD42b.
RRID:
AB_2841724
引用格式: Affinity Biosciences Cat# DF8519, RRID:AB_2841724.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Antigen CD42b alpha; BDPLT1; BDPLT3; BSS; CD 42b; CD42b alpha; CD42B; CD42b antigen; DBPLT3; GLYCOCALICIN; Glycoprotein Ib (platelet) alpha polypeptide; Glycoprotein Ibalpha; GP Ib alpha; GP1B; GP1BA; GPIb alpha; GPIbA; MGC34595; Platelet glycoprotein Ib alpha chain; Platelet glycoprotein Ib alpha polypeptide; Platelet membrane glycoprotein 1b alpha subunit; VWDP;

抗原和靶标

免疫原:

A synthesized peptide derived from human CD42b, corresponding to a region within C-terminal amino acids.

基因/基因ID:
GP1BA(2811)

研究领域

· Environmental Information Processing > Signaling molecules and interaction > ECM-receptor interaction.   (View pathway)

· Organismal Systems > Immune system > Platelet activation.   (View pathway)

· Organismal Systems > Immune system > Hematopoietic cell lineage.   (View pathway)

文献引用

1). Engineered exosome nanovesicles for delivery of antibodies to treat inflammatory bowel disease. Nature Communications, 2026 (PubMed: 41688436) [IF=15.7]

Application: WB    Species: Mouse    Sample: exosomes

Fig. 2 | Preparation and characterization of PrEXO-a23. (e) Western blot analysis of protein markers in rEXO, PMV, a23, and PrEXO-a23.
2). Curcumin-loaded milk-derived sEVs fused with platelet membrane attenuate endothelial senescence and promote spinal cord injury recovery in diabetic mice. Materials today. Bio, 2025 (PubMed: 40688662) [IF=8.7]

Application: WB    Species: Mouse    Sample:

Fig. 4. Preparation and characterization of PM-sEVs. (A) Typical TEM images of sEVs and PM-sEVs. Both sEVs and PM-sEVs exhibited characteristic cup-shaped morphology. Scale bar = 100 nm. (B, C) Size distribution of sEVs and PM-sEVs by NTA analysis. sEVs and PM-sEVs exhibited similar size distributions. (D) Typical images of PM-sEVs, DiO-labeled sEVs, DiL-labeled PM. Scale bar = 20 μm. The co-localization (yellow signals) of DiO (sEVs) and DiL (PM) fluorescence indicates successful fusion. (E) Analysis of Tsg-101, Alix, CD9, GPIbα, Integrin β1 and Integrin α2 expression of sEVs, PM-sEVs and PM by WB. Note: (1) sEVs markers (Tsg101, Alix, CD9) were enriched in both sEVs and PM-sEVs. (2) PM markers (GPIbα, Integrin β1, Integrin α2) were expressed in PM and PM-sEVs, but absent (or very low) in sEVs, confirming the incorporation of PM proteins onto PM-sEVs. (F) Typical images of DiO-labeled sEVs and PM-sEVs incubated with HUVECs. Scale bar = 20 μm. The significantly enhanced cellular uptake of DiO-PM-sEVs compared to that of DiO-sEVs demonstrated the improved targeting efficiency mediated by the PM coating. (G) IVIS images showing the distribution of sEVs, PM-sEVs and PM in the spinal cord. The fluorescence intensity was higher at the SCI site in the PM-sEVs group than in the sEVs group. (H) Cur release kinetics. The sustained release kinetics of Cur from PM-sEVs-Cur and sEVs-Cur were compared to the faster release of Cur alone. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)

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