NPC1L1 Antibody - #DF8449

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产品: NPC1L1 抗体
货号: DF8449
描述: Rabbit polyclonal antibody to NPC1L1
应用: WB IF/ICC
文献验证: WB
反应: Human
预测: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus
蛋白号: Q9UHC9
RRID: AB_2841689

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:1000-3000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
克隆:
Polyclonal
特异性:
NPC1L1 Antibody detects endogenous levels of total NPC1L1.
RRID:
AB_2841689
引用格式: Affinity Biosciences Cat# DF8449, RRID:AB_2841689.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Niemann Pick C1 like protein 1; Niemann Pick disease type C1 gene like 1; Niemann-Pick C1-like protein 1; NPC1 LIKE 1; NPC1 Niemann Pick disease type C1 gene like 1; NPC1L1; NPC1L1 splice variant; NPCL1_HUMAN; Truncated Niemann Pick C1 like protein 1;

抗原和靶标

免疫原:

A synthesized peptide derived from human NPC1L1, corresponding to a region within N-terminal amino acids.

基因/基因ID:
NPC1L1(29881)

研究领域

· Organismal Systems > Digestive system > Fat digestion and absorption.

文献引用

1). Evaluating the Effects of Perinatal Exposures to BPSIP on Hepatic Cholesterol Metabolism in Female and Male Offspring ICR Mice. Environmental health perspectives, 2024 (PubMed: 39298647) [IF=10.1]

Application: WB    Species: human    Sample:

Figure 4. The effects of BPSIP, BPS, or E2 exposure on the regulation of hepatic cholesterol biosynthesis and intestinal absorption in offspring mice. Liver qPCR analysis of selected cholesterol biosynthesis key genes in (A) females and (B) males (𝑁=24, 𝑛=6 per group/sex). Immunoblotting of liver HMGCR in (C) females and (D) males (𝑁=28, 𝑛=7/group for female; 𝑁=32, 𝑛=8/group for male). (E) Immunofluorescence staining of HMGCR in livers of female offspring mice (the scale bar=50μ⁢m). (F) Quantification for HMGCR per filed in females (𝑁=12, 𝑛=6 per group). (G) Immunofluorescence staining of HMGCR in livers of male offspring mice (the scale bar=50μ⁢m). (H) Quantification for HMGCR per filed in males (𝑁=12, 𝑛=6 per group). Intestinal qPCR of Npc1l1 and Mttp in (I) females and (J) males (𝑁=32, 𝑛=8 per group/sex). Immunoblotting of intestinal NPC1L1 in (K) females and (L) males (𝑁=28, 𝑛=7 per group/sex). All data were provided as means±SEM. Statistical analysis was performed using Student’s 𝑡-test (F,H) and one-way ANOVA followed by post hoc Tukey’s test (A–D,I–L). *𝑝

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