HPD Antibody - #DF8303

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产品: HPD 抗体
货号: DF8303
描述: Rabbit polyclonal antibody to HPD
应用: WB
反应: Human, Mouse, Rat
预测: Rabbit
分子量: 45 kDa; 45kD(Calculated).
蛋白号: P32754
RRID: AB_2841585

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Rabbit(100%)
克隆:
Polyclonal
特异性:
HPD Antibody detects endogenous levels of total HPD.
RRID:
AB_2841585
引用格式: Affinity Biosciences Cat# DF8303, RRID:AB_2841585.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

4 HPPD; 4 hydroxyphenylpyruvate dioxygenase; 4 hydroxyphenylpyruvic acid oxidase; 4-hydroxyphenylpyruvate dioxygenase; 4-hydroxyphenylpyruvic acid oxidase; 4HPPD; GLOD3; glyoxalase domain containing 3; HPD; HPPD_HUMAN; HPPDase; PPD;

抗原和靶标

免疫原:
Uniprot:

P32754(HPPD_HUMAN) >>Visit HPA database.

基因/基因ID:
HPD(3242)
序列:
MTTYSDKGAKPERGRFLHFHSVTFWVGNAKQAASFYCSKMGFEPLAYRGLETGSREVVSHVIKQGKIVFVLSSALNPWNKEMGDHLVKHGDGVKDIAFEVEDCDYIVQKARERGAKIMREPWVEQDKFGKVKFAVLQTYGDTTHTLVEKMNYIGQFLPGYEAPAFMDPLLPKLPKCSLEMIDHIVGNQPDQEMVSASEWYLKNLQFHRFWSVDDTQVHTEYSSLRSIVVANYEESIKMPINEPAPGKKKSQIQEYVDYNGGAGVQHIALKTEDIITAIRHLRERGLEFLSVPSTYYKQLREKLKTAKIKVKENIDALEELKILVDYDEKGYLLQIFTKPVQDRPTLFLEVIQRHNHQGFGAGNFNSLFKAFEEEQNLRGNLTNMETNGVVPGM

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Rabbit
100
Pig
0
Horse
0
Bovine
0
Sheep
0
Dog
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - P32754 作为底物

Site PTM Type Enzyme
T2 Acetylation
Y4 Phosphorylation
K63 Ubiquitination
Y105 Phosphorylation
K127 Ubiquitination
S211 Phosphorylation
Y221 Phosphorylation
S222 Phosphorylation
S223 Phosphorylation
S226 Phosphorylation
Y232 Phosphorylation
K247 Acetylation
K249 Ubiquitination
S290 Phosphorylation
Y295 Phosphorylation
Y296 Phosphorylation
K297 Ubiquitination
K311 Ubiquitination
T382 Phosphorylation

研究背景

功能:

Key enzyme in the degradation of tyrosine.

亚基结构:

Homodimer.

蛋白家族:

Belongs to the 4HPPD family.

研究领域

· Metabolism > Metabolism of cofactors and vitamins > Ubiquinone and other terpenoid-quinone biosynthesis.

· Metabolism > Amino acid metabolism > Tyrosine metabolism.

· Metabolism > Amino acid metabolism > Phenylalanine metabolism.

· Metabolism > Global and overview maps > Metabolic pathways.

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