| 产品: | GFPT1 抗体 |
| 货号: | DF8232 |
| 描述: | Rabbit polyclonal antibody to GFPT1 |
| 应用: | WB IHC |
| 反应: | Human, Rat |
| 预测: | Pig, Bovine, Horse, Rabbit, Dog, Chicken |
| 分子量: | 79 kDa; 79kD(Calculated). |
| 蛋白号: | Q06210 |
| RRID: | AB_2841529 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF8232, RRID:AB_2841529.
展开/折叠
CMS12; CMSTA1; D-fructose-6-phosphate amidotransferase 1; GFA; GFAT 1; GFAT; GFAT1; GFAT1m; GFPT; Gfpt1; GFPT1_HUMAN; GFPT1L; Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1; Glutamine--fructose-6-phosphate transaminase 1; Glutamine:fructose 6 phosphate amidotransferase 1; Hexosephosphate aminotransferase 1; MSLG;
抗原和靶标
Isoform 1 is predominantly expressed in skeletal muscle. Not expressed in brain. Seems to be selectively expressed in striated muscle.
- Q06210 GFPT1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MCGIFAYLNYHVPRTRREILETLIKGLQRLEYRGYDSAGVGFDGGNDKDWEANACKIQLIKKKGKVKALDEEVHKQQDMDLDIEFDVHLGIAHTRWATHGEPSPVNSHPQRSDKNNEFIVIHNGIITNYKDLKKFLESKGYDFESETDTETIAKLVKYMYDNRESQDTSFTTLVERVIQQLEGAFALVFKSVHFPGQAVGTRRGSPLLIGVRSEHKLSTDHIPILYRTARTQIGSKFTRWGSQGERGKDKKGSCNLSRVDSTTCLFPVEEKAVEYYFASDASAVIEHTNRVIFLEDDDVAAVVDGRLSIHRIKRTAGDHPGRAVQTLQMELQQIMKGNFSSFMQKEIFEQPESVVNTMRGRVNFDDYTVNLGGLKDHIKEIQRCRRLILIACGTSYHAGVATRQVLEELTELPVMVELASDFLDRNTPVFRDDVCFFLSQSGETADTLMGLRYCKERGALTVGITNTVGSSISRETDCGVHINAGPEIGVASTKAYTSQFVSLVMFALMMCDDRISMQERRKEIMLGLKRLPDLIKEVLSMDDEIQKLATELYHQKSVLIMGRGYHYATCLEGALKIKEITYMHSEGILAGELKHGPLALVDKLMPVIMIIMRDHTYAKCQNALQQVVARQGRPVVICDKEDTETIKNTKRTIKVPHSVDCLQGILSVIPLQLLAFHLAVLRGYDVDFPRNLAKSVTVE
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q06210 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| C2 | S-Nitrosylation | Uniprot | |
| K25 | Ubiquitination | Uniprot | |
| K48 | Ubiquitination | Uniprot | |
| K56 | Ubiquitination | Uniprot | |
| S103 | Phosphorylation | Uniprot | |
| K139 | Ubiquitination | Uniprot | |
| T149 | Phosphorylation | Uniprot | |
| K154 | Ubiquitination | Uniprot | |
| K157 | Ubiquitination | Uniprot | |
| K190 | Ubiquitination | Uniprot | |
| T201 | Phosphorylation | Uniprot | |
| S205 | Phosphorylation | P17612 (PRKACA) | Uniprot |
| K216 | Ubiquitination | Uniprot | |
| S235 | Phosphorylation | P17612 (PRKACA) | Uniprot |
| S242 | Phosphorylation | Q13131 (PRKAA1) | Uniprot |
| K251 | Ubiquitination | Uniprot | |
| S253 | Phosphorylation | Uniprot | |
| S257 | Phosphorylation | Uniprot | |
| S261 | Phosphorylation | Q13131 (PRKAA1) , Q9UQM7 (CAMK2A) | Uniprot |
| T262 | Phosphorylation | Uniprot | |
| T263 | Phosphorylation | Uniprot | |
| Y275 | Phosphorylation | Uniprot | |
| Y276 | Phosphorylation | Uniprot | |
| K345 | Ubiquitination | Uniprot | |
| Y367 | Phosphorylation | Uniprot | |
| T368 | Phosphorylation | Uniprot | |
| K375 | Ubiquitination | Uniprot | |
| T467 | Phosphorylation | Uniprot | |
| S470 | Phosphorylation | Uniprot | |
| S473 | Phosphorylation | Uniprot | |
| C478 | S-Nitrosylation | Uniprot | |
| K536 | Ubiquitination | Uniprot | |
| K547 | Acetylation | Uniprot | |
| K547 | Ubiquitination | Uniprot | |
| Y553 | Phosphorylation | Uniprot | |
| S557 | Phosphorylation | Uniprot | |
| K640 | Ubiquitination | Uniprot | |
| K650 | Acetylation | Uniprot | |
| K694 | Ubiquitination | Uniprot | |
| S695 | Phosphorylation | Uniprot |
研究背景
Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins. Regulates the circadian expression of clock genes ARNTL/BMAL1 and CRY1.
Isoform 1 is predominantly expressed in skeletal muscle. Not expressed in brain. Seems to be selectively expressed in striated muscle.
Homotetramer (Probable), may also exist as homodimers.
研究领域
· Human Diseases > Endocrine and metabolic diseases > Insulin resistance.
· Metabolism > Amino acid metabolism > Alanine, aspartate and glutamate metabolism.
· Metabolism > Carbohydrate metabolism > Amino sugar and nucleotide sugar metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
限制条款
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