产品: TSPO 抗体
货号: DF8227
描述: Rabbit polyclonal antibody to TSPO
应用: WB IHC IF/ICC
文献验证: IHC, IF/ICC
反应: Human, Mouse
预测: Dog
蛋白号: P30536
RRID: AB_2841527

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse
克隆:
Polyclonal
特异性:
TSPO Antibody detects endogenous levels of total TSPO.
RRID:
AB_2841527
引用格式: Affinity Biosciences Cat# DF8227, RRID:AB_2841527.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Benzodiazapine receptor (peripheral); Benzodiazepine peripheral binding site; BPBS; BZRP; DBI; IBP; Isoquinoline carboxamide-binding protein; MBR; mDRC; Mitochondrial benzodiazepine receptor; PBR; PBS; Peripheral benzodiazepine receptor; Peripheral benzodiazepine receptor-related protein; Peripheral type benzodiazepine receptor; Peripheral-type benzodiazepine receptor; pk18; PKBS; PTBR; Ptbzr; PTBZR02; RATPTBZR02; translocator protein (18kDa); Translocator protein; Tspo; Tspo1; TSPOA_HUMAN;

抗原和靶标

免疫原:

A synthesized peptide derived from human TSPO, corresponding to a region within C-terminal amino acids.

基因/基因ID:

研究领域

· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.

· Human Diseases > Infectious diseases: Viral > HTLV-I infection.

· Organismal Systems > Digestive system > Cholesterol metabolism.

文献引用

1). Fibroblast Activation Protein Acts as a Biomarker for Monitoring ECM Remodeling During Aortic Aneurysm via 68Ga-FAPI-04 PET Imaging. Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025 (PubMed: 39950910) [IF=15.1]

Application: IF/ICC    Species: rabbit    Sample:

Figure 6 Histological and western blot analyses confirm the temporal changes of tissue FAP levels during AAA progression. A) The outcomes of H&E, EVG, Masson blue staining, and immunohistochemical examinations of TSPO and vimentin of specimens from the indicated groups of New Zealand rabbits. B) The medial thickness of aortic specimens from the indicated groups of New Zealand rabbits. C,D) Immunofluorescence analysis (C) and its quantification (D) of TSPO (green) from the indicated groups of New Zealand rabbits. E) Immunofluorescence analysis, investigating the co-expression of FAP and α-SMA, among the indicated groups of New Zealand rabbits. F) Co-localization analysis of FAP and α-SMA in the medial layer of the aorta among the indicated groups of New Zealand rabbits. The red line indicated α-SMA expression, while the green line represented FAP expression. G,H) The western blot of FAP, OPN, and α-SMA (G) and its quantification (H) in the indicated groups of New Zealand rabbits. *p < 0.05, **p < 0.01, and ***p < 0.001, ns, not statistically significant. TSPO, Translocator protein.

2). The soluble epoxide hydrolase inhibitor TPPU improves comorbidity of chronic pain and depression via the AHR and TSPO signaling. Journal of translational medicine, 2023 (PubMed: 36732752) [IF=7.4]

3). Inflammatory Immune Process and Depression-like Behavior in Hypothyroid Rats: A [18F] DPA-714 Micro Positron Emission Tomography Study. Pharmaceuticals, 2023 (PubMed: 37259424) [IF=4.6]

Application: IHC    Species: Rat    Sample: hippocampus

Figure 5. Immunohistochemical results of TSPO, Iba-1, NLRP3 expression (Under 40× optical microscope). Brown cells are positive (as shown by the black arrow) and blue cells are negative.

4). Design of a deuterated TSPO tracer and its application in glioma and atherosclerotic imaging. New Journal of Chemistry, 2025 [IF=2.7]

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