SOX18 Antibody - #DF8018

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产品: SOX18 抗体
货号: DF8018
描述: Rabbit polyclonal antibody to SOX18
应用: WB
文献验证: WB
反应: Human, Mouse, Rat
预测: Bovine, Dog
蛋白号: P35713
RRID: AB_2841390

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
SOX18 Antibody detects endogenous levels of total SOX18.
RRID:
AB_2841390
引用格式: Affinity Biosciences Cat# DF8018, RRID:AB_2841390.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

HLTS; SOX 18; Sox18; SOX18_HUMAN; SRY (sex determining region Y) box 18; SRY box 18; Transcription factor SOX 18; Transcription factor SOX-18;

抗原和靶标

免疫原:

A synthesized peptide derived from human SOX18, corresponding to a region within N-terminal amino acids.

基因/基因ID:
SOX18(54345)

文献引用

1). SOX18 enhances the proliferation and migration of airway smooth muscle cells induced by tumor necrosis factor-α via the regulation of Notch1 signaling. International Immunopharmacology, 2021 (PubMed: 34004439) [IF=4.8]

Application: WB    Species: mouse    Sample: airway smooth muscle cells

Fig. 2. |Knockdown of SOX18 impeded the proliferation and migration of airway smooth muscle cells induced by tumor necrosis factor-α (TNF-α). Airway smooth muscle cells were transfected with scrambled short hairpin RNA (shRNA) or SOX18 shRNA constructs and cultivated for 48 h prior to TNF-α stimulation for another 24 h.(B, C) Levels of the SOX18 protein were determined via western blotting (N = 3).
2). SOX18 exerts tumor-suppressive functions in papillary thyroid carcinoma through inhibition of Wnt/β-catenin signaling. EXPERIMENTAL CELL RESEARCH, 2020 (PubMed: 32858034) [IF=3.3]

Application: WB    Species: human    Sample: papillary thyroid carcinoma

Fig. 1.| Analysis of SOX18 expression in papillary thyroid carcinoma tissues and cell lines.(C, D)Protein expression of SOX18 in clinical specimens of papillary thyroid carcinoma was determined by Western blot. **p < 0.01.

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