GRN Antibody - #DF7997

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产品: GRN 抗体
货号: DF7997
描述: Rabbit polyclonal antibody to GRN
应用: WB IHC IF/ICC
文献验证: WB, IHC
反应: Human, Mouse, Rat, Monkey
预测: Bovine, Horse, Sheep, Rabbit, Dog
蛋白号: P28799
RRID: AB_2841380

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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相关下载
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:1000-3000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat, Monkey
克隆:
Polyclonal
特异性:
GRN Antibody detects endogenous levels of total GRN.
RRID:
AB_2841380
引用格式: Affinity Biosciences Cat# DF7997, RRID:AB_2841380.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Acrogranin; CLN11; GEP; GP88; Granulin A; Granulin B; Granulin C; Granulin D; Granulin E; Granulin epithelin; Granulin F; Granulin G; Granulin-7; Granulins; GRN; GRN_HUMAN; PC cell derived growth factor; PCDGF; PEPI; PGRN; Proepithelin; Progranulin;

抗原和靶标

免疫原:

A synthesized peptide derived from human GRN, corresponding to a region within the internal amino acids.

基因/基因ID:
GRN(2896)

文献引用

1). Identification of potential ferroptosis-associated biomarkers in rheumatoid arthritis. Frontiers in Immunology, 2023 (PubMed: 37492576) [IF=5.7]

Application: WB    Species: Human    Sample:

Figure 13 Validation of the hub genes in experimental samples. (A) Representative tracing of the PI and the joint swelling thickness in rat after CFA or Nor treatment in the two groups(n=12). (B) Representative images of H&E staining of joint sections from AIA rat or Nor rat. (C) The expression of GRN, PTGS2 and ENO1. n = 3. *p < 0.05, **p < 0.01, ***p < 0.001. (D) IHC staining for PTGS2, ENO1, and GRN on synovium from samples of OA and RA patients (n = 3).

Application: IHC    Species: Human    Sample:

Figure 13 Validation of the hub genes in experimental samples. (A) Representative tracing of the PI and the joint swelling thickness in rat after CFA or Nor treatment in the two groups(n=12). (B) Representative images of H&E staining of joint sections from AIA rat or Nor rat. (C) The expression of GRN, PTGS2 and ENO1. n = 3. *p < 0.05, **p < 0.01, ***p < 0.001. (D) IHC staining for PTGS2, ENO1, and GRN on synovium from samples of OA and RA patients (n = 3).
2). PGRN knockdown alleviates pulmonary fibrosis regulating the Akt/GSK3β signaling pathway. International immunopharmacology, 2025 (PubMed: 40088870) [IF=4.8]
3). Physical exercise mitigates the cognitive impairments by promoting ER-phagy in mice model of Alzheimer's disease. Behavioural brain research, 2025 (PubMed: 40414310) [IF=2.6]
4). Granulin in renal tubular epithelia is associated with interstitial inflammation and activates the TLR9-IFN-α pathway in lupus nephritis. Lupus, 2024 (PubMed: 38334360) [IF=1.9]

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