CKB Antibody - #DF7930

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产品: CKB 抗体
货号: DF7930
描述: Rabbit polyclonal antibody to CKB
应用: WB
反应: Human, Mouse, Rat
预测: Pig, Bovine, Horse, Rabbit, Dog, Chicken, Xenopus
分子量: 43 kDa; 43kD(Calculated).
蛋白号: P12277
RRID: AB_2841341

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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MSDS
说明书
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实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Pig(100%), Bovine(100%), Horse(100%), Rabbit(100%), Dog(100%), Chicken(100%), Xenopus(100%)
克隆:
Polyclonal
特异性:
CKB Antibody detects endogenous levels of total CKB.
RRID:
AB_2841341
引用格式: Affinity Biosciences Cat# DF7930, RRID:AB_2841341.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

B CK; B-CK; BB-CK; BCK; Brain creatine kinase; Ckb; CKBB; Creatine kinase B; Creatine kinase B chain; Creatine kinase B type; Creatine kinase B-type; Creatine Kinase BB Isoenzyme; Creatine kinase brain; Creatine kinase brain type; Creatine phosphokinase BB; Epididymis luminal protein 211; Epididymis secretory protein Li 29; HEL 211; HEL S 29; KCRB_HUMAN;

抗原和靶标

免疫原:
Uniprot:

P12277(KCRB_HUMAN) >>Visit HPA database.

基因/基因ID:
CKB(1152)
序列:
MPFSNSHNALKLRFPAEDEFPDLSAHNNHMAKVLTPELYAELRAKSTPSGFTLDDVIQTGVDNPGHPYIMTVGCVAGDEESYEVFKDLFDPIIEDRHGGYKPSDEHKTDLNPDNLQGGDDLDPNYVLSSRVRTGRSIRGFCLPPHCSRGERRAIEKLAVEALSSLDGDLAGRYYALKSMTEAEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKTFLVWVNEEDHLRVISMQKGGNMKEVFTRFCTGLTQIETLFKSKDYEFMWNPHLGYILTCPSNLGTGLRAGVHIKLPNLGKHEKFSEVLKRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEQRLEQGQAIDDLMPAQK

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Dog
100
Xenopus
100
Chicken
100
Rabbit
100
Sheep
0
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - P12277 作为底物

Site PTM Type Enzyme
S4 Phosphorylation
S6 Phosphorylation
K11 Ubiquitination
R13 Methylation
S24 Phosphorylation
K32 Ubiquitination
T35 Phosphorylation
Y39 Phosphorylation
R43 Methylation
K45 Ubiquitination
Y82 Phosphorylation
K86 Ubiquitination
R96 Methylation
K101 Ubiquitination
K107 Ubiquitination
T108 Phosphorylation
Y125 Phosphorylation
S128 Phosphorylation
T133 Phosphorylation
S136 Phosphorylation
R138 Methylation
K156 Ubiquitination
S164 Phosphorylation
R172 Methylation
Y173 Phosphorylation
Y174 Phosphorylation
S178 Phosphorylation
K196 Ubiquitination
S199 Phosphorylation
R215 Methylation
K223 Sumoylation
K223 Ubiquitination
K242 Ubiquitination
K247 Ubiquitination
C254 S-Nitrosylation
T255 Phosphorylation
K265 Ubiquitination
K267 Acetylation
Y269 Phosphorylation
Y279 Phosphorylation
S285 Phosphorylation
K298 Ubiquitination
K304 Ubiquitination
K307 Sumoylation
K307 Ubiquitination
S309 Phosphorylation
K313 Acetylation
K313 Ubiquitination
R320 Methylation
T322 Phosphorylation
T327 Phosphorylation
S337 Phosphorylation
K381 Ubiquitination

研究背景

功能:

Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.

细胞定位:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
亚基结构:

Dimer of identical or non-identical chains, which can be either B (brain type) or M (muscle type). With MM being the major form in skeletal muscle and myocardium, MB existing in myocardium, and BB existing in many tissues, especially brain.

蛋白家族:

Belongs to the ATP:guanido phosphotransferase family.

研究领域

· Metabolism > Amino acid metabolism > Arginine and proline metabolism.

· Metabolism > Global and overview maps > Metabolic pathways.

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