产品: TMPRSS2 抗体
货号: DF7917
描述: Rabbit polyclonal antibody to TMPRSS2
应用: WB IHC
文献验证: WB
反应: Human, Mouse
预测: Pig, Bovine, Horse, Dog
蛋白号: O15393
RRID: AB_2841332

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse
克隆:
Polyclonal
特异性:
TMPRSS2 Antibody detects endogenous levels of total TMPRSS2.
RRID:
AB_2841332
引用格式: Affinity Biosciences Cat# DF7917, RRID:AB_2841332.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

D16Ertd61e; Epitheliasin; FLJ41954; MGC6821; PP9284; PRSS10; Serine protease 10; TMPRSS2; TMPRSS2 ERG FUSION GENE, INCLUDED; TMPRSS2 ETV1 FUSION GENE, INCLUDED; TMPS2_HUMAN; Transmembrane protease serine 2 catalytic chain; Transmembrane protease, serine 2; Transmembrane protease, serine 2, EC 3.4.219;

抗原和靶标

免疫原:

A synthesized peptide derived from human TMPRSS2, corresponding to a region within the internal amino acids.

基因/基因ID:

研究领域

· Human Diseases > Infectious diseases: Viral > Influenza A.

· Human Diseases > Cancers: Overview > Transcriptional misregulation in cancer.

· Human Diseases > Cancers: Specific types > Prostate cancer.   (View pathway)

文献引用

1). Revealing the mechanism of ethyl acetate extracts of Semen Impatientis against prostate cancer based on network pharmacology and transcriptomics. Journal of ethnopharmacology, 2024 (PubMed: 38643863) [IF=4.8]

Application: WB    Species: Human    Sample:

Fig. 6. Network pharmacology analysis and experiments were utilized to explore the molecular mechanism of EAESI in PCa. (A) Disease-related targets for PCa were selected from DrugBank, GeneCards, OMIM, and the TTD. (B) Venn diagram showing the intersection of the drug targets and the disease-related targets. (C) A compound–target network was constructed. (D) The common targets of Semen Impatientis and PCa were used to construct the PPI network. (E) Topological analysis of the PPI network was employed to identify the hub genes. (F–G) The impacts of EAESI on the expression and transcriptional activity of AR in LNCaP and 22RV1 cells were evaluated by RT‒qPCR (F) and Western blot (G) assays. The data are presented as the means ± SDs. *P < 0.05, **P < 0.01, ***P < 0.001 compared with the 0 mg/mL group.

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