产品: Hemoglobin subunit alpha 抗体
货号: DF7893
描述: Rabbit polyclonal antibody to Hemoglobin subunit alpha
应用: WB IF/ICC
反应: Human
预测: Pig, Zebrafish, Bovine, Horse, Sheep, Dog, Chicken
分子量: 15 kDa, 25 kDa; 15kD(Calculated).
蛋白号: P69905
RRID: AB_2841314

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
WB 1:1000-3000, IF/ICC 1:200-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
预测:
Pig(100%), Zebrafish(82%), Bovine(100%), Horse(100%), Sheep(100%), Dog(92%), Chicken(100%)
克隆:
Polyclonal
特异性:
Hemoglobin subunit alpha Antibody detects endogenous levels of total Hemoglobin subunit alpha.
RRID:
AB_2841314
引用格式: Affinity Biosciences Cat# DF7893, RRID:AB_2841314.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Alpha 1 globin; Alpha globin; Alpha one globin; Alpha-globin; HBA_HUMAN; HBA1; HBA2; Hemoglobin alpha 1; Hemoglobin alpha 1 chain; Hemoglobin alpha 1 globin chain; Hemoglobin alpha 2; Hemoglobin alpha chain; Hemoglobin subunit alpha; MGC126895; MGC126897;

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
表达:
P69905 HBA_HUMAN:

Red blood cells.

序列:
MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR

种属预测

种属预测:

score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Chicken
100
Dog
92
Zebrafish
82
Xenopus
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - P69905 作为底物

Site PTM Type Enzyme
S4 O-Glycosylation
S4 Phosphorylation
K8 Acetylation
T9 Phosphorylation
K12 Acetylation
K17 Acetylation
K17 Ubiquitination
Y25 Phosphorylation
S36 O-Glycosylation
S36 Phosphorylation
T39 Phosphorylation
T40 Phosphorylation
K41 Acetylation
K41 Ubiquitination
T42 Phosphorylation
Y43 Phosphorylation
S50 Phosphorylation
S53 Phosphorylation
K57 Acetylation
K57 Ubiquitination
K61 Acetylation
K61 Ubiquitination
K62 Acetylation
S82 Phosphorylation
K91 Acetylation
K100 Acetylation
C105 S-Nitrosylation
T109 Phosphorylation
S132 Phosphorylation
S134 O-Glycosylation
T135 Phosphorylation
T138 Phosphorylation
S139 Phosphorylation
K140 Acetylation
Y141 Phosphorylation

研究背景

功能:

Involved in oxygen transport from the lung to the various peripheral tissues.

翻译修饰:

The initiator Met is not cleaved in variant Thionville and is acetylated.

组织特异性:

Red blood cells.

亚基结构:

Heterotetramer of two alpha chains and two beta chains in adult hemoglobin A (HbA); two alpha chains and two delta chains in adult hemoglobin A2 (HbA2); two alpha chains and two epsilon chains in early embryonic hemoglobin Gower-2; two alpha chains and two gamma chains in fetal hemoglobin F (HbF).

(Microbial infection) Interacts with Staphylococcus aureus protein isdB.

蛋白家族:

Belongs to the globin family.

研究领域

· Human Diseases > Infectious diseases: Parasitic > African trypanosomiasis.

· Human Diseases > Infectious diseases: Parasitic > Malaria.

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