DAB2 Antibody - #DF7792

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产品: DAB2 抗体
货号: DF7792
描述: Rabbit polyclonal antibody to DAB2
应用: WB IHC IF/ICC
文献验证: WB, IF/ICC
反应: Human, Mouse
预测: Pig, Bovine, Sheep, Rabbit, Dog, Xenopus
蛋白号: P98082
RRID: AB_2841249

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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MS Report
HPLC Report
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
IHC 1:50-1:200, WB 1:1000-3000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse
克隆:
Polyclonal
特异性:
DAB2 Antibody detects endogenous levels of total DAB2.
RRID:
AB_2841249
引用格式: Affinity Biosciences Cat# DF7792, RRID:AB_2841249.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

DAB 2; Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila); DAB2; Differentially expressed in ovarian cancer 2; Differentially expressed protein 2; Disabled (Drosophila) homolog 2 (mitogen responsive phosphoprotein); Disabled homolog 2; Disabled homolog 2 mitogen responsive phosphoprotein (Drosophila); Disabled homolog 2 mitogen responsive phosphoprotein; Disabled, Drosophila, homolog of, 2; DOC 2; DOC2; FLJ26626; Mitogen responsive phosphoprotein;

抗原和靶标

免疫原:

A synthesized peptide derived from human DAB2, corresponding to a region within C-terminal amino acids.

基因/基因ID:
DAB2(1601)

研究领域

· Cellular Processes > Transport and catabolism > Endocytosis.   (View pathway)

文献引用

1). DAB2 promotes pulmonary fibrosis and may act as an intermediate between IGF‑1R and PI3K/AKT signaling pathways. Experimental and Therapeutic Medicine, 2023 (PubMed: 37021069) [IF=2.4]

Application: WB    Species: Human    Sample: MRC-5 cells

Figure 2 Knockdown of DAB2 inhibits TGF-β1-induced proliferation of MRC-5 cells. Myofibroblast differentiation of MRC-5 cells (human embryonic lung fibroblasts) under TGF-β1 induction for 24 h. (A) Immunofluorescence staining of DAB2 in MRC-5 cells with TGF-β1 treatment (scale bar, 50 µm). (B) Relative mRNA level of DAB2 in TGF-β1-treated MRC-5 cells. ***P

Application: IF/ICC    Species: Human    Sample: MRC-5 cells

Figure 1 Expression of DAB2 is significantly upregulated in the bleomycin-induced fibrotic lung tissue. (A-C) Results from differential gene expression analysis based on Gene Expression Omnibus database. Lung samples from mice treated with saline (Control group) or bleomycin (BLM group) were set in GSE8553. (A) Volcano plot showing 244 differentially expressed genes with blue dots representing downregulated genes (Log2FC

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