Histone H1 Antibody - #AF0876
| 产品: | Histone H1 抗体 |
| 货号: | AF0876 |
| 描述: | Rabbit polyclonal antibody to Histone H1 |
| 应用: | WB IF/ICC |
| 反应: | Human, Rat |
| 预测: | Bovine, Sheep |
| 分子量: | 21kDa; 36kD(Calculated). |
| 蛋白号: | Q8IZA3 |
| RRID: | AB_2834405 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# AF0876, RRID:AB_2834405.
展开/折叠
H1 histone family member O oocyte specific; H1FOO; H1FOO_HUMAN; Histone H1oo; Oocyte-specific histone H1; Oocyte-specific linker histone H1; osH1;
抗原和靶标
- Q8IZA3 H1FOO_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAPGSVTSDISPSSTSTAGSSRSPESEKPGPSHGGVPPGGPSHSSLPVGRRHPPVLRMVLEALQAGEQRRGTSVAAIKLYILHKYPTVDVLRFKYLLKQALATGMRRGLLARPLNSKARGATGSFKLVPKHKKKIQPRKMAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPKPGAATEKARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSSQGDAEAYRKTKAESKSSKPTASKVKNGAASPTKKKVVAKAKAPKAGQGPNTKAAAPAKGSGSKVVPAHLSRKTEAPKGPRKAGLPIKASSSKVSSQRAEA
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q8IZA3 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T7 | Phosphorylation | Uniprot | |
| S26 | Phosphorylation | Uniprot | |
| R147 | Methylation | Uniprot | |
| K153 | Acetylation | Uniprot | |
| K155 | Acetylation | Uniprot | |
| K158 | Acetylation | Uniprot | |
| K205 | Methylation | Uniprot | |
| S245 | Phosphorylation | Uniprot | |
| S246 | Phosphorylation | Uniprot | |
| Y253 | Phosphorylation | Uniprot |
研究背景
May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling (By similarity).
Cytoplasm. Nucleus. Chromosome.
Oocyte-specific.
Belongs to the histone H1/H5 family.
限制条款
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