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| 产品: | 乙酰化Lysine 抗体 |
| 货号: | DF7729 |
| 描述: | Rabbit polyclonal antibody to Acetyl-Lysine |
| 应用: | WB |
| 文献验证: | WB |
| 反应: | Human, All |
| 蛋白号: | |
| RRID: | AB_2841197 |
产品描述
来源:
Rabbit
应用:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
反应:
Human, All
克隆:
Polyclonal
特异性:
Acetyl-Lysine Antibody detects endogenous levels of Acetyl-Lysine Antibody only when acetylated at Lysine Antibody.
RRID:
AB_2841197
引用格式: Affinity Biosciences Cat# DF7729, RRID:AB_2841197.
引用格式: Affinity Biosciences Cat# DF7729, RRID:AB_2841197.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
抗原和靶标
免疫原:
A synthesized peptide derived from human Lysine Antibody around the acetylation site of Lysine Antibody.
文献引用
1). Trilobatin suppresses aging-induced cognitive impairment by targeting SIRT2: Involvement of remodeling gut microbiota to mediate the brain-gut axis. Phytomedicine : international journal of phytotherapy and phytopharmacology, 2024
(PubMed: 38763011)
[IF=6.7]
2). LncRNA HOTAIRM1 promotes radioresistance in nasopharyngeal carcinoma by modulating FTO acetylation-dependent alternative splicing of CD44. Neoplasia (New York, N.Y.), 2024
(PubMed: 39128424)
[IF=6.3]
3). Sirt3 Rescues Porphyromonas gingivalis-Impaired Cementogenesis via SOD2 Deacetylation. Cell proliferation, 2025
(PubMed: 40068967)
[IF=5.9]
4). Rosmarinic Acid Alleviates Radiation-Induced Pulmonary Fibrosis by Downregulating the tRNA N7-Methylguanosine Modification-Regulated Fibroblast-to-Myofibroblast Transition Through the Exosome Pathway. Journal of inflammation research, 2024
(PubMed: 39188632)
[IF=4.5]
5). Resveratrol ameliorates triglyceride accumulation through FXR deacetylation in high glucose-treated HepG2 cells. Journal of Functional Foods, 2023
[IF=3.8]
Application: WB Species: Human Sample: HepG2 cells
Fig. 4. Effect of resveratrol on the acetylation of FXR in HepG2 cells. (A) The interaction of SIRT1 with FXR. (B) The relative protein levels of Ac-FXR in different groups of HepG2 cells detected by IP.
6). GRIM-19 inhibits proliferation and induces apoptosis in a p53-dependent manner in colorectal cancer cells through the SIRT7/PCAF/MDM2 axis. Experimental Cell Research, 2021
(PubMed: 34461110)
[IF=3.3]
Application: WB Species: Human Sample: CRC cells
Fig. 1. GRIM-19 expression is related to CRC progression. (A) Expression of GRIM-19 transcript in CRC tissues versus adjacent normal tissues. The plotted data
are from the GEPIA database. (B and C) Overall survival and disease-free survival among CRC patients with different GRIM-19 levels. The plotted data are from the
GEPIA database. (D and E) The expression of GRIM-19 and p53 in primary normal colorectal (N) and CRC (T) tissues as analyzed by Western blot assays. (F and G)
The expression of GRIM-19 in normal colorectal and CRC tissues was detected by IHC. Bar = 50 μ m. (H) The expression of GRIM-19 in CRC cell lines DLD-1, SW620,
HT15, HCT116 and HCT-8 as analyzed by Western blot assays.
7). Curcumol alleviates liver fibrosis by inducing endoplasmic reticulum stress-mediated necroptosis of hepatic stellate cells through Sirt1/NICD pathway. PeerJ, 2022
(PubMed: 35582617)
[IF=2.3]
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