产品: Ferritin Heavy Chain 抗体
货号: DF7705
描述: Rabbit polyclonal antibody to Ferritin Heavy Chain
应用: WB IF/ICC
文献验证: WB
反应: Human
预测: Pig, Bovine, Horse, Rabbit, Dog, Xenopus
蛋白号: P02794
RRID: AB_2841175

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
WB 1:1000-3000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
克隆:
Polyclonal
特异性:
Ferritin Heavy Chain Antibody detects endogenous levels of total Ferritin Heavy Chain.
RRID:
AB_2841175
引用格式: Affinity Biosciences Cat# DF7705, RRID:AB_2841175.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Apoferritin; Cell proliferation inducing gene 15 protein; Cell proliferation-inducing gene 15 protein; F HC; Ferritin H subunit; Ferritin heavy chain; Ferritin heavy polypeptide 1; FHC; FRIH; FRIH_HUMAN; FTH 1; FTH; FTH1; FTH1 protein; FTHL 6; FTHL6; Iron overload autosomal dominant; MGC104426; N-terminally processed; OK/SW-cl.84; PIG 15; PIG15; Placenta immunoregulatory factor; PLIF; Proliferation inducing gene 15 protein; Proliferation inducing protein 15;

抗原和靶标

免疫原:

A synthesized peptide derived from human Ferritin Heavy Chain, corresponding to a region within C-terminal amino acids.

基因/基因ID:

研究领域

· Cellular Processes > Cell growth and death > Ferroptosis.   (View pathway)

· Cellular Processes > Cell growth and death > Necroptosis.   (View pathway)

· Organismal Systems > Digestive system > Mineral absorption.

文献引用

1). Hsa_circ_0002301 inhibits ferroptosis in gastric cancer by encoding the de novo protein HECTD1-463aa. Journal of translational medicine, 2025 (PubMed: 40022084) [IF=7.4]

Application: WB    Species: Mouse    Sample:

Fig. 1 Elevated hsa_circ_0002301 expression is correlated with ferroptosis in a gastric cancer model.a. A mouse gastric cancer model induced by N-methyl-N-nitrosourea (MNU) was established. b. Ferroptosis indicators, such as Fe2+ accumulation, MDA levels, ROS levels, and the GSH/GSSG ratio, were assessed in the three groups. c. FNR protein expression was assessed in adjacent nontumor tissues and gastric cancer tissues from mice. (d) Tumor sections were spread for volume and weight measurements. (e) Hematoxylin and eosin (H&E) staining revealed the histopathological morphology of gastric cancer tissues with high ferroptosis levels, while Ki-67 staining revealed the cell proliferation capacity. Scale bar: 100 μm. (f) Expression of the 7 selected circRNAs in 46 pairs of gastric cancer and adjacent tissues from clinical samples obtained during surgery. The graph shows the mean ± standard deviation (SD) values; *p 

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