TUBGCP5 Antibody - #AF0621
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# AF0621, RRID:AB_2834398.
展开/折叠
Gamma tubulin complex component GCP5; Gamma-tubulin complex component 5; GCP 5; GCP-5; GCP5; GCP5_HUMAN; KIAA1899; OTTHUMP00000159254; Tubgcp5; Tubulin gamma complex associated protein 5;
抗原和靶标
Widely expressed, with highest levels in heart and skeletal muscle and moderate levels in brain.
- Q96RT8 GCP5_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MARHGPPWSRLDAQQERDVRELVRGVAGLQDEADPNFQLALNFAWSNFRFHRFLDVNSHKIEKTIEGIYEKFVIHSDLSKAASWKRLTEEFLNAPLPSIKEIKTDAHYSILSLLLCLSDSPSNSSYVETPRNKEVEKKDDFDWGKYLMEDEEMDIGPYMDTPNWSEESEEENDQQPLSREDSGIQVDRTPLEEQDQNRKLDPCISWKDEPDDRSWLEHHVVHQYWTARPSQFPHSLHLHSNLAAVWDQHLYSSDPLYVPDDRVLVTETQVIRETLWLLSGVKKLFIFQLIDGKVTVRNNIIVTHLTHSCLRSVLEQIAAYGQVVFRLQEFIDEVMGHSSESMLPGSGSVPKKSTEAPFRTYQAFMWALYKYFISFKEELAEIEKCIINNDTTITLAIVVDKLAPRLSQLKVLHKVFSTGVAEVPPDTRNVVRASHLLNTLYKAILEYDNVGEASEQTVSLLFSLWVETVRPYLQTVDEWIVHGHLWDGAREFIIQRNKNVPVNHRDFWYATYTLYSVSEKTENEEKMSDNASASSGSDQGPSSRQHTMVSFLKPVLKQIIMAGKSMQLLKNLQCAESTTCQAGARDAERKSLYTLFLESVQSRLRHGEDSTPQVLTEQQATKENLMKMQSIAESHLELDDVHDPLLAINFARMYLEQSDFHEKFAGGDVCVDRSSESVTCQTFELTLRSCLYPHIDKQYLDCCGNLMQTLKKDYRLVEYLQAMRNFFLMEGGDTMYDFYTSIFDKIREKETWQNVSFLNVQLQEAVGQRYPEDSSRLSISFENVDTAKKKLPVHILDGLTLSYKVPWPVDIVISLECQKIYNQVFLLLLQIKWAKYSLDVLLFGELVSTAEKPRLKEGLIHEQDTVAQFGPQKEPVRQQIHRMFLLRVKLMHFVNSLHNYIMTRILHSTGLEFQHQVEEAKDLDQLIKIHYRYLSTIHDRCLLREKVSFVKEAIMKVLNLALMFADGWQAGLGTWRMESIEKMESDFKNCHMFLVTILNKAVCRGSFPHLESLALSLMAGMEQS
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q96RT8 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K63 | Ubiquitination | Uniprot | |
| Y69 | Phosphorylation | Uniprot | |
| S83 | Phosphorylation | Uniprot | |
| K100 | Ubiquitination | Uniprot | |
| K138 | Ubiquitination | Uniprot | |
| S182 | Phosphorylation | Uniprot | |
| R188 | Methylation | Uniprot | |
| S205 | Phosphorylation | Uniprot | |
| S346 | Phosphorylation | Uniprot | |
| S348 | Phosphorylation | Uniprot | |
| S407 | Phosphorylation | Uniprot | |
| K410 | Ubiquitination | Uniprot | |
| K526 | Ubiquitination | Uniprot | |
| S528 | Phosphorylation | Uniprot | |
| S532 | Phosphorylation | Uniprot | |
| S535 | Phosphorylation | Uniprot | |
| K553 | Ubiquitination | Uniprot | |
| K564 | Ubiquitination | Uniprot | |
| K570 | Ubiquitination | Uniprot | |
| K590 | Ubiquitination | Uniprot | |
| T611 | Phosphorylation | Uniprot | |
| K622 | Ubiquitination | Uniprot | |
| S630 | Phosphorylation | Uniprot | |
| S658 | Phosphorylation | Uniprot | |
| K663 | Ubiquitination | Uniprot | |
| K697 | Ubiquitination | Uniprot | |
| K711 | Ubiquitination | Uniprot | |
| K788 | Ubiquitination | Uniprot | |
| K789 | Ubiquitination | Uniprot | |
| K856 | Ubiquitination | Uniprot | |
| K873 | Ubiquitination | Uniprot |
研究背景
Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
Cytoplasm>Cytoskeleton>Microtubule organizing center>Centrosome.
Widely expressed, with highest levels in heart and skeletal muscle and moderate levels in brain.
Gamma-tubulin complex is composed of gamma-tubulin, TUBGCP2, TUBGCP3, TUBGCP4, TUBGCP5 and TUBGCP6.
Belongs to the TUBGCP family.
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