产品: MST1/STK4 抗体
货号: DF7691
描述: Rabbit polyclonal antibody to MST1/STK4
应用: WB IHC
文献验证: WB, IHC
反应: Human, Mouse
预测: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken
蛋白号: Q13043
RRID: AB_2841162

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse
克隆:
Polyclonal
特异性:
MST-1/STK4 Antibody detects endogenous levels of total MST-1/STK4.
RRID:
AB_2841162
引用格式: Affinity Biosciences Cat# DF7691, RRID:AB_2841162.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Kinase responsive to stress; Krs2; Mammalian STE20 like protein kinase 1; Mammalian STE20-like protein kinase 1; Mammalian sterile 20 like 1; MST-1; MST1; Serine/threonine kinase 4; Serine/threonine protein kinase Krs 2; Serine/threonine-protein kinase 4; Serine/threonine-protein kinase Krs-2; STE20 like kinase MST1; STE20-like kinase MST1; STK4; STK4_HUMAN; TIIAC; YSK3;

抗原和靶标

免疫原:

A synthesized peptide derived from human STK4, corresponding to a region within C-terminal amino acids.

基因/基因ID:

研究领域

· Environmental Information Processing > Signal transduction > MAPK signaling pathway.   (View pathway)

· Environmental Information Processing > Signal transduction > Ras signaling pathway.   (View pathway)

· Environmental Information Processing > Signal transduction > FoxO signaling pathway.   (View pathway)

· Human Diseases > Cancers: Overview > Pathways in cancer.   (View pathway)

· Human Diseases > Cancers: Specific types > Non-small cell lung cancer.   (View pathway)

文献引用

1). Curcumol inhibits the viability and invasion of colorectal cancer cells via miR‑30a‑5p and Hippo signaling pathway. Oncology Letters, 2021 (PubMed: 33732375) [IF=2.5]

Application: WB    Species: Human    Sample: CRC tissue

Figure 1. miR-30a-5p expression and Hippo signaling pathway activity in CRC tissue samples. miR-30a-5p expression in (A) six pairs of CRC and paracancerous tissues, and (B) CRC cell lines was analyzed by RT-qPCR. (C) Expression levels of epithelial-mesenchymal transition, MMP2 and Hippo signaling pathway-associated proteins in three pairs of CRC and paracancerous tissues were analyzed by western blotting. (D) Semi-quantitative analysis of the results of western blotting. RT-qPCR and western blotting data are presented as the mean ± standard deviation of three independent experiments. *P<0.05 and **P<0.01 vs. control (normal or HCoEpic). miR, microRNA; RT-qPCR, reverse transcription-quantitative PCR; CRC, colorectal cancer; MST-1, mammalian STE20-like protein kinase; LATS1, large tumor suppressor kinase 1; YAP1, Yes-associated protein; p, phosphorylated; N, normal tissue; T, tumor tissue.

2). Identification and validation of a novel innate lymphoid cell-based signature to predict prognosis and immune response in liver cancer by integrated single-cell RNA analysis and bulk RNA sequencing. Translational cancer research, 2024 (PubMed: 39525025) [IF=1.5]

Application: IHC    Species: human    Sample:

Figure 12. The expression of the five key ILC genes verified by IHC. Representative 100× IHC images of (A) STK4, CALM1, (B) C2, RORA, and IL7R in different T stages of HCC. ILC, innate lymphoid cell; IHC, immunohistochemistry; HCC, hepatocellular carcinoma.

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