HDAC7 Antibody - #AF0180

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产品: HDAC7 抗体
货号: AF0180
描述: Rabbit polyclonal antibody to HDAC7
应用: WB IHC IF/ICC
文献验证: WB, IHC
反应: Human, Mouse, Rat
预测: Pig, Bovine, Horse, Sheep, Dog
蛋白号: Q8WUI4
RRID: AB_2833373

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:3000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
HDAC7 Antibody detects endogenous levels of total HDAC7.
RRID:
AB_2833373
引用格式: Affinity Biosciences Cat# AF0180, RRID:AB_2833373.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

DKFZP586J0917; FLJ99588; HD 7a; HD7; HD7a; HDAC 7; HDAC 7A; Hdac7; HDAC7_HUMAN; HDAC7A; Histone deacetylase 7; Histone deacetylase 7A; OTTHUMP00000202813; OTTHUMP00000202814;

抗原和靶标

免疫原:

A synthesized peptide derived from human HDAC7, corresponding to a region within the internal amino acids.

基因/基因ID:
HDAC7(51564)
描述:
HDAC7 Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes

研究领域

· Human Diseases > Substance dependence > Alcoholism.

· Human Diseases > Infectious diseases: Viral > Human papillomavirus infection.

· Human Diseases > Cancers: Overview > Viral carcinogenesis.

文献引用

1). Self-activated arsenic manganite nanohybrids for visible and synergistic thermo/immuno-arsenotherapy. Journal of Controlled Release, 2022 (PubMed: 36063961) [IF=10.5]
2). Modified Xiao-Qing-Long-decoction prevents inflammation and promotes Nur77 expression in mice with acute respiratory distress syndrome by inhibiting HDAC7 expression. Pharmaceutical biology, 2025 (PubMed: 39902793) [IF=3.9]

Application: IHC    Species: Mouse    Sample:

Figure 4. MXQLD treatment suppressed HDAC7 expression but increased Nur77 expression in ARDS mice. (A) Immunohistochemical analysis was applied to detect the protein expression of HDAC7 in the lung tissues of mice. Original magnification × 200; scale bar = 100 μm; original magnification × 200; scale bar = 50 μm. n = 3. (B) Western blot analysis was used to measure protein expressions of HDAC7 and Nur77 in the lung tissues of mice. n = 3. Results were presented as mean ± SD.

Application: WB    Species: Mouse    Sample:

Figure 4. MXQLD treatment suppressed HDAC7 expression but increased Nur77 expression in ARDS mice. (A) Immunohistochemical analysis was applied to detect the protein expression of HDAC7 in the lung tissues of mice. Original magnification × 200; scale bar = 100 μm; original magnification × 200; scale bar = 50 μm. n = 3. (B) Western blot analysis was used to measure protein expressions of HDAC7 and Nur77 in the lung tissues of mice. n = 3. Results were presented as mean ± SD.

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