LAT Antibody - #DF7630

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产品: LAT 抗体
货号: DF7630
描述: Rabbit polyclonal antibody to LAT
应用: WB IF/ICC
文献验证: WB
反应: Human, Mouse
预测: Pig, Zebrafish, Bovine, Horse, Sheep
蛋白号: O43561
RRID: AB_2841115

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:1000-3000, IF/ICC 1:200-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse
克隆:
Polyclonal
特异性:
LAT Antibody detects endogenous levels of total LAT.
RRID:
AB_2841115
引用格式: Affinity Biosciences Cat# DF7630, RRID:AB_2841115.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

36 kDa phospho tyrosine adapter protein; 36 kDa phospho-tyrosine adapter protein; 36 kDa phospho-tyrosine adaptor protein; LAT 1; lat; LAT_HUMAN; LAT1; Linker for activation of T cells; Linker for activation of T cells family member 1; linker for activation of T cells, transmembrane adaptor; Linker for activation of T-cells family member 1; p36 38; p36-38; pp36;

抗原和靶标

免疫原:

A synthesized peptide derived from human LAT, corresponding to a region within the internal amino acids.

基因/基因ID:
LAT(27040)

研究领域

· Environmental Information Processing > Signal transduction > Ras signaling pathway.   (View pathway)

· Environmental Information Processing > Signal transduction > Rap1 signaling pathway.   (View pathway)

· Environmental Information Processing > Signal transduction > NF-kappa B signaling pathway.   (View pathway)

· Organismal Systems > Immune system > Natural killer cell mediated cytotoxicity.   (View pathway)

· Organismal Systems > Immune system > Th1 and Th2 cell differentiation.   (View pathway)

· Organismal Systems > Immune system > Th17 cell differentiation.   (View pathway)

· Organismal Systems > Immune system > T cell receptor signaling pathway.   (View pathway)

· Organismal Systems > Immune system > Fc epsilon RI signaling pathway.   (View pathway)

· Organismal Systems > Immune system > Fc gamma R-mediated phagocytosis.   (View pathway)

文献引用

1). Endometrial regenerative cells with galectin-9 high-expression attenuate experimental autoimmune hepatitis. Stem cell research & therapy, 2021 (PubMed: 34654474) [IF=7.5]

Application: WB    Species: Mouse    Sample:

Fig. 7 Inhibition of T cell proliferation by Gal-9 high-expressing ERCs is associated with Lck/ZAP70/LAT pathway. The naïve CD4+ T cells in the mouse spleen were collected by magnetic bead, and then the harvested CD4+ T cells were co-cultured with unmodified ERCs or Gal-9 high-expressing ERCs for 6 days. A CD4+ T cell proliferation was determined by CCK-8 assay. B The protein expressions and phosphorylation form protein expressions of Lck, ZAP-70, LAT were detected by western blot. The differences between groups were calculated by using ANOVA. *p 

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