PAX6 Antibody - #DF7557

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产品: PAX6 抗体
货号: DF7557
描述: Rabbit polyclonal antibody to PAX6
应用: WB IHC IF/ICC
文献验证: WB
反应: Human, Mouse, Rat
预测: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
蛋白号: P26367
RRID: AB_2841051

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
IF/ICC 1:100-1:500, WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
PAX6 Antibody detects endogenous levels of total PAX6.
RRID:
AB_2841051
引用格式: Affinity Biosciences Cat# DF7557, RRID:AB_2841051.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

AN 2; AN; AN2; Aniridia type II protein; D11S812E; FVH1; KIAA0552; Leucine zipper putative tumor suppressor 3; LZTS3; MGC17209; MGDA; Oculorhombin; Paired box 6; Paired box gene 6 (aniridia keratitis); Paired Box Gene 6; Paired box homeotic gene 6; Paired box protein Pax-6; Paired box protein Pax6; PAX 6; PAX6; PAX6_HUMAN; ProSAP-interacting protein 1; PROSAPIP1; Sey; WAGR;

抗原和靶标

免疫原:

A synthesized peptide derived from human PAX6, corresponding to a region within the internal amino acids.

基因/基因ID:
PAX6(5080)

研究领域

· Cellular Processes > Cellular community - eukaryotes > Signaling pathways regulating pluripotency of stem cells.   (View pathway)

· Human Diseases > Endocrine and metabolic diseases > Maturity onset diabetes of the young.

文献引用

1). Long non-coding RNA (lncRNA) PGM5P4-AS1 inhibits lung cancer progression by up-regulating Leucine Zipper Tumor Suppressor (LZTS3) through sponging microRNA miR-1275. Bioengineered, 2020 (PubMed: 33315502) [IF=4.2]

Application: WB    Species: Human    Sample: A549 cells

Figure 5. PGM5P4-AS1 decreased the miR-1275 level and promoted the expression of LZTS3. (a-b), Relative expression levels of miRNA-1275 and LZTS3 in A549 cells, that were interfered in PGM5P4-AS1 expression (**p < 0.01 vs. NC siRNA). (c-d), Relative expression levels of miRNA-1275 and LZTS3 in SK-MES-1 cells, that were overexpressed of PGM5P4-AS1 (##p < 0.01 vs. vector). (e-f), Protein expression levels of LZTS3, cyclinD1, MMP-2, Bcl-2, and Bcl-xl in A549 cells, that were transfected with PGM5P4-AS1 siRNA or PGM5P4-AS1-OE, respectively (**p < 0.01 vs. NC siRNA, ##p < 0.01 vs. vector).
2). Generation of an induced pluripotent stem cell (iPSC) line (IGIBi026-A) derived from Wilson disease patient harboring compound heterozygous mutations [c.2165dupT (p.R723Efs31) and c.C813A (p.C271*)] in the ATP7B gene. Stem cell research, 2024 (PubMed: 39326255) [IF=1.2]

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