产品: LATS2 抗体
货号: DF7516
描述: Rabbit polyclonal antibody to LATS2
应用: WB IHC
文献验证: WB
反应: Human, Mouse, Rat
预测: Pig, Horse, Rabbit, Dog
蛋白号: Q9NRM7
RRID: AB_2841015

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   规格 价格 库存
 50ul RMB¥ 1500 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
LATS2 Antibody detects endogenous levels of total LATS2.
RRID:
AB_2841015
引用格式: Affinity Biosciences Cat# DF7516, RRID:AB_2841015.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

FLJ13161; Kinase phosphorylated during mitosis protein; KPM; Large tumor suppressor homolog 2; Large tumor suppressor homolog 2 Drosophila; Large tumor suppressor kinase 2; LATS large tumor suppressor Drosophila homolog 2; LATS large tumor suppressor homolog 2; Lats2; LATS2_HUMAN; Serine/threonine kinase kpm; Serine/threonine protein kinase kpm; Serine/threonine-protein kinase kpm; Serine/threonine-protein kinase LATS2; Warts like kinase; Warts-like kinase;

抗原和靶标

免疫原:

A synthesized peptide derived from human LATS2, corresponding to a region within the internal amino acids.

基因/基因ID:

研究领域

· Environmental Information Processing > Signal transduction > Hippo signaling pathway.   (View pathway)

· Environmental Information Processing > Signal transduction > Hippo signaling pathway - multiple species.   (View pathway)

文献引用

1). ZNF143 facilitates the growth and migration of glioma cells by regulating KPNA2-mediated Hippo signalling. Scientific reports, 2023 (PubMed: 37423952) [IF=3.8]

2). Identification of key genes and pathways in endometriosis by integrated expression profiles analysis. PeerJ, 2021 (PubMed: 33354413) [IF=2.3]

Application: WB    Species: Human    Sample:

Figure 7 Dysregulation of Hippo signaling pathway in EC. (A) Schematic diagram of the Hippo signaling pathway. The key genes of interest are marked in red. (Image credit: the KEGG archive at https://www.kegg.jp). (B) Western blotting was performed to detect the expression and phosphorylation of Hippo signaling pathway proteins in EC, EU and NE.

3). Effect of e-cigarette refill liquid on follicular development and estrogen secretion in rats. Tobacco Induced Diseases, 2022 (PubMed: 35529323) [IF=2.2]

Application: WB    Species: Rat    Sample:

Figure 4 Western blot analysis of control, 0.05 mg and 0.5 mg groups of 21- (A) and 35-day-old (B) rat ovaries. Pictures C, D are the relative grey values analysis of CYP19, YAP, PYAP, LATS2, PLATS2 in each group compared with β-actin. Picture C is 21-day-old rat ovaries and D is 35-day-old rat ovaries. Picture E is the estrogen concentration (pg/mL) in each group of 21- and 35-day-old rat ovaries determined by ELISA.

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