| 产品: | DNAJC15 抗体 |
| 货号: | DF2918 |
| 描述: | Rabbit polyclonal antibody to DNAJC15 |
| 应用: | WB IHC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| 分子量: | 16kDa; 16kD(Calculated). |
| 蛋白号: | Q9Y5T4 |
| RRID: | AB_2840906 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF2918, RRID:AB_2840906.
展开/折叠
Cell growth inhibiting gene 22 protein; Cell growth-inhibiting gene 22 protein; DJC15_HUMAN; DnaJ (Hsp40) homolog subfamily C member 15; DNAJ domain containing; DnaJ homolog subfamily C member 15; DNAJC15; DNAJD1; GIG22; HSD18; MCJ; Methylation controlled J protein; Methylation-controlled J protein;
抗原和靶标
- Q9Y5T4 DJC15_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAARGVIAPVGESLRYAEYLQPSAKRPDADVDQQRLVRSLIAVGLGVAALAFAGRYAFRIWKPLEQVITETAKKISTPSFSSYYKGGFEQKMSRREAGLILGVSPSAGKAKIRTAHRRVMILNHPDKGGSPYVAAKINEAKDLLETTTKH
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
研究背景
Negative regulator of the mitochondrial respiratory chain. Prevents mitochondrial hyperpolarization state and restricts mitochondrial generation of ATP (By similarity). Acts as an import component of the TIM23 translocase complex. Stimulates the ATPase activity of HSPA9.
Mitochondrion inner membrane>Single-pass membrane protein.
Expressed at highest levels in heart, followed by liver and kidney.
Interacts with the TIM23 complex. Directly interacts with PAM16/MAGMAS; this interaction counteracts DNAJC15-dependent stimulation of HSPA9 ATPase activity. Associates with complex I of the mitochondrial electron transfer chain; this interaction may interfere with the formation of supercomplexes that facilitate the transfer of electrons between complexes (By similarity).
限制条款
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