产品: COLEC12 抗体
货号: DF10165
描述: Rabbit polyclonal antibody to COLEC12
应用: WB IHC
文献验证: WB
反应: Human, Mouse, Rat
预测: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
蛋白号: Q5KU26
RRID: AB_2840744

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
COLEC12 Antibody detects endogenous levels of total COLEC12.
RRID:
AB_2840744
引用格式: Affinity Biosciences Cat# DF10165, RRID:AB_2840744.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

CL P1; CL-P1; CLP1; COL12_HUMAN; COLEC 12; colec12; Collectin placenta 1; Collectin placenta protein 1; Collectin sub family member 12; Collectin-12; hCL P1; hCL-P1; NSR2; Nurse cell scavenger receptor 2; SCARA4; Scavenger receptor class A member 4; Scavenger receptor with C type lectin; Scavenger receptor with C-type lectin; SRCL;

抗原和靶标

免疫原:

A synthesized peptide derived from human COLEC12, corresponding to a region within C-terminal amino acids.

基因/基因ID:

研究领域

· Cellular Processes > Transport and catabolism > Phagosome.   (View pathway)

文献引用

1). Integrated bioinformatics analyses of key genes involved in hepatocellular carcinoma immunosuppression. Oncology Letters, 2021 (PubMed: 34691257) [IF=2.5]

Application: WB    Species: Human    Sample: liver tissues and HCC tissues

Figure 4. Validation of COLEC12, MMP12 and MUC12 mRNA and protein levels. (A) Comparison of COLEC12 mRNA levels between HCC tissues (n=17) and cirrhosis (n=20) or normal liver tissues (n=6) in the GEO datasets (GSE17548 and GSE83148), and immunohistochemical staining of COLEC12 in HCC tissues and normal liver tissues downloaded from the Human Protein Atlas. (B) The comparisons of the MMP12 mRNA level between HCC tissues and cirrhosis or normal liver tissues in the GEO datasets (GSE17548 and GSE83148). (C) The comparisons of the MUC12 mRNA level between HCC tissues and cirrhosis or normal liver tissues in the GEO datasets (GSE17548 and GSE83148), and immunohistochemical staining of MUC12 in HCC tissues and normal liver tissues downloaded from the Human Protein Atlas. (D) The comparisons of the mRNA and protein expression levels of COLEC12, MUC12 and MMP12 between tumor samples (HCC tissues, n=4) and normal (corresponding adjacent normal liver tissues, n=4) samples of HCC patients from the Second Affiliated Hospital of Nanchang University. *P<0.05 and **P<0.01 vs. normal or cirrhosis, respectively. COLEC12, collectin-12 gene, MMP12, matrix metalloproteinase-12 gene; MUC12, mucin-12 gene; HCC, hepatocellular carcinoma; GEO, Gene Expression Omnibus.

Application: WB    Species: Human    Sample: HCC tissues and normal liver tissues

Figure 4. Validation of COLEC12, MMP12 and MUC12 mRNA and protein levels. (A) Comparison of COLEC12 mRNA levels between HCC tissues (n=17) and cirrhosis (n=20) or normal liver tissues (n=6) in the GEO datasets (GSE17548 and GSE83148), and immunohistochemical staining of COLEC12 in HCC tissues and normal liver tissues downloaded from the Human Protein Atlas. (B) The comparisons of the MMP12 mRNA level between HCC tissues and cirrhosis or normal liver tissues in the GEO datasets (GSE17548 and GSE83148). (C) The comparisons of the MUC12 mRNA level between HCC tissues and cirrhosis or normal liver tissues in the GEO datasets (GSE17548 and GSE83148), and immunohistochemical staining of MUC12 in HCC tissues and normal liver tissues downloaded from the Human Protein Atlas. (D) The comparisons of the mRNA and protein expression levels of COLEC12, MUC12 and MMP12 between tumor samples (HCC tissues, n=4) and normal (corresponding adjacent normal liver tissues, n=4) samples of HCC patients from the Second Affiliated Hospital of Nanchang University. *P<0.05 and **P<0.01 vs. normal or cirrhosis, respectively. COLEC12, collectin-12 gene, MMP12, matrix metalloproteinase-12 gene; MUC12, mucin-12 gene; HCC, hepatocellular carcinoma; GEO, Gene Expression Omnibus.

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