| 产品: | PSD4 抗体 |
| 货号: | DF10161 |
| 描述: | Rabbit polyclonal antibody to PSD4 |
| 应用: | WB |
| 反应: | Human |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 116kDa; 116kD(Calculated). |
| 蛋白号: | Q8NDX1 |
| RRID: | AB_2840740 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF10161, RRID:AB_2840740.
展开/折叠
EFA6B; Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B; FLJ36237; FLJ37279; PH and SEC7 domain-containing protein 4; Pleckstrin homology and SEC7 domain-containing protein 4; Ppleckstrin and Sec7 domain containing 4; PSD4; PSD4_HUMAN; SEC7 homolog antibody | telomeric of interleukin-1 cluster protein; Telomeric of interleukin-1 cluster protein; TIC;
抗原和靶标
Widely expressed. Highest levels of expression are found in placenta, pancreas, spleen, thymus and peripheral blood.
- Q8NDX1 PSD4_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MMGDYRLPDHPQPMEILNLYLGDSLEPHPGECPRETCSHEDPPEPFEEQTWATDPPEPTRQNVPPWGSGVELTHLGSWVHQDGLEPCQEQTRATDPPESTRQDAPPWGSGVELTHLGSPSAQREHRQNTASPGSPVNSHLPGSPKQNRSTSTQVVFWAGILQAQMCVLDLEEELEKTEGLKAGLKCCLPTPPVDLPGDTGLHSSPPENEDSGEDSSEPEGEGQAWLREGTPDSSPQWGAEEESMFFSNPLFLASPCSENSASGECFSWGASDSHAGVRTGPESPATLEPPLPEDTVLWELESEPDLGDGAAISGHCTPPFPVPIYKPHSICWASVAAAEGAPAAPPGHGESEGDRLGPAPSAAPCVDEALTWESGCVGSDLGPAAHPVQPWASLSPEGWQRGGPFWPQVTLNSQDRDEREGGHPQESLPCTLAPCPWRSPASSPEPSSPESESRGPGPRPSPASSQEGSPQLQHHSSGILPKWTLDASQSSLLETDGEQPSSLKKKEAGEAPKPGEEVKSEGTARPAETGDVQPDIHLTSAEHENLRTPMNSSWLPGSPMPQAQSPEEGQRPPAGDKLANGVRNNKVAWNLASRLYRLEGFRKSEVAAYLQKNNDFSRAVAEEYLSFFQFGGQSLDRALRSFLQALVLSGETQERERILYQFSRRFHHCNPGIFPSVDSVHTLTCAIMLLNTDLHGQNIGKSMSCQEFITNLNGLRDGGNFPKELLKALYWSIRSEKLEWAVDEEDTARPEKAQPSLPAGKMSKPFLQLAQDPTVPTYKQGILARKMHQDADGKKTPWGKRGWKMFHTLLRGMVLYFLKQGEDHCLEGESLVGQMVDEPVGVHHSLATPATHYTKKPHVFQLRTADWRLYLFQAPTAKEMSSWIARINLAAATHSAPPFPAAVGSQRRFVRPILPVGPAQSSLEEQHRSHENCLDAAADDLLDLQRNLPERRGRGRELEEHRLRKEYLEYEKTRYETYVQLLVARLHCPSDALDLWEEQLGREAGGTREPKLSLKKSHSSPSLHQDEAPTTAKVKRNISERRTYRKIIPKRNRNQL
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q8NDX1 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T50 | Phosphorylation | Uniprot | |
| S68 | Phosphorylation | Uniprot | |
| S77 | Phosphorylation | Uniprot | |
| S109 | Phosphorylation | Uniprot | |
| T114 | Phosphorylation | Uniprot | |
| S118 | Phosphorylation | Uniprot | |
| S131 | Phosphorylation | Uniprot | |
| S134 | Phosphorylation | Uniprot | |
| S138 | Phosphorylation | Uniprot | |
| S143 | Phosphorylation | Uniprot | |
| K181 | Ubiquitination | Uniprot | |
| T230 | Phosphorylation | Uniprot | |
| S233 | Phosphorylation | Uniprot | |
| T317 | Phosphorylation | Uniprot | |
| S395 | Phosphorylation | Uniprot | |
| T410 | Phosphorylation | Uniprot | |
| S413 | Phosphorylation | Uniprot | |
| S448 | Phosphorylation | Uniprot | |
| S461 | Phosphorylation | Uniprot | |
| S464 | Phosphorylation | Uniprot | |
| S465 | Phosphorylation | Uniprot | |
| S469 | Phosphorylation | Uniprot | |
| S488 | Phosphorylation | Uniprot | |
| S490 | Phosphorylation | Uniprot | |
| S491 | Phosphorylation | Uniprot | |
| T495 | Phosphorylation | Uniprot | |
| S501 | Phosphorylation | Uniprot | |
| S502 | Phosphorylation | Uniprot | |
| T548 | Phosphorylation | Uniprot | |
| S558 | Phosphorylation | Uniprot | |
| S565 | Phosphorylation | Uniprot | |
| K586 | Ubiquitination | Uniprot | |
| K603 | Ubiquitination | Uniprot | |
| K723 | Ubiquitination | Uniprot | |
| K752 | Ubiquitination | Uniprot | |
| K761 | Ubiquitination | Uniprot | |
| S763 | Phosphorylation | Uniprot | |
| K764 | Ubiquitination | Uniprot | |
| K779 | Ubiquitination | Uniprot | |
| K786 | Ubiquitination | Uniprot | |
| T808 | Phosphorylation | Uniprot | |
| Y816 | Phosphorylation | Uniprot | |
| S905 | Phosphorylation | Uniprot | |
| Y975 | Phosphorylation | Uniprot | |
| S1013 | Phosphorylation | Uniprot | |
| K1016 | Ubiquitination | Uniprot | |
| S1017 | Phosphorylation | Uniprot | |
| S1019 | Phosphorylation | Uniprot | |
| S1020 | Phosphorylation | Uniprot | |
| S1022 | Phosphorylation | Uniprot | |
| T1031 | Phosphorylation | Uniprot | |
| S1039 | Phosphorylation | Uniprot | |
| T1043 | Phosphorylation | Uniprot | |
| K1046 | Ubiquitination | Uniprot |
研究背景
Guanine nucleotide exchange factor for ARF6 and ARL14/ARF7. Through ARL14 activation, controls the movement of MHC class II-containing vesicles along the actin cytoskeleton in dendritic cells. Involved in membrane recycling. Interacts with several phosphatidylinositol phosphate species, including phosphatidylinositol 3,4-bisphosphate, phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 4,5-bisphosphate.
Cell membrane. Cell projection>Ruffle membrane.
Note: In interphase associated with the plasma membrane, in particular with membrane ruffling regions (PubMed:23603394). Accumulates in dynamic actin-rich membrane ruffles and microvilli-like structures (PubMed:12082148). Recruited to membranes via phosphatidylinositol phosphate-binding (Probable).
Widely expressed. Highest levels of expression are found in placenta, pancreas, spleen, thymus and peripheral blood.
研究领域
· Cellular Processes > Transport and catabolism > Endocytosis. (View pathway)
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