ADNP Antibody - #AF0418

(1)  
产品: ADNP 抗体
货号: AF0418
描述: Rabbit polyclonal antibody to ADNP
应用: WB IF/ICC
反应: Human, Mouse
预测: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken
分子量: 124kDa; 124kD(Calculated).
蛋白号: Q9H2P0
RRID: AB_2834336

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse
预测:
Pig(92%), Bovine(83%), Horse(92%), Sheep(83%), Rabbit(100%), Dog(92%), Chicken(83%)
克隆:
Polyclonal
特异性:
ADNP Antibody detects endogenous levels of total ADNP.
RRID:
AB_2834336
引用格式: Affinity Biosciences Cat# AF0418, RRID:AB_2834336.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Activity dependent neuroprotective protein; Activity dependent neuroprotector; Activity-dependent neuroprotective protein; Activity-dependent neuroprotector homeobox protein; Adnp; ADNP_HUMAN; KIAA0784;

抗原和靶标

免疫原:
Uniprot:

Q9H2P0(ADNP_HUMAN) >>Visit HPA database.

基因/基因ID:
ADNP(23394)
表达:
Q9H2P0 ADNP_HUMAN:

Widely expressed. Strong expression in heart, skeletal muscle, kidney and placenta. In brain, expression is stronger in the cerebellum and cortex regions. No expression detected in the colon. Strong increase of expression in colon and breast cancer tissues.

描述:
ADNP Potential transcription factor. May mediate some of the neuroprotective peptide VIP-associated effects involving normal growth and cancer proliferation.
序列:
MFQLPVNNLGSLRKARKTVKKILSDIGLEYCKEHIEDFKQFEPNDFYLKNTTWEDVGLWDPSLTKNQDYRTKPFCCSACPFSSKFFSAYKSHFRNVHSEDFENRILLNCPYCTFNADKKTLETHIKIFHAPNASAPSSSLSTFKDKNKNDGLKPKQADSVEQAVYYCKKCTYRDPLYEIVRKHIYREHFQHVAAPYIAKAGEKSLNGAVPLGSNAREESSIHCKRCLFMPKSYEALVQHVIEDHERIGYQVTAMIGHTNVVVPRSKPLMLIAPKPQDKKSMGLPPRIGSLASGNVRSLPSQQMVNRLSIPKPNLNSTGVNMMSSVHLQQNNYGVKSVGQGYSVGQSMRLGLGGNAPVSIPQQSQSVKQLLPSGNGRSYGLGSEQRSQAPARYSLQSANASSLSSGQLKSPSLSQSQASRVLGQSSSKPAAAATGPPPGNTSSTQKWKICTICNELFPENVYSVHFEKEHKAEKVPAVANYIMKIHNFTSKCLYCNRYLPTDTLLNHMLIHGLSCPYCRSTFNDVEKMAAHMRMVHIDEEMGPKTDSTLSFDLTLQQGSHTNIHLLVTTYNLRDAPAESVAYHAQNNPPVPPKPQPKVQEKADIPVKSSPQAAVPYKKDVGKTLCPLCFSILKGPISDALAHHLRERHQVIQTVHPVEKKLTYKCIHCLGVYTSNMTASTITLHLVHCRGVGKTQNGQDKTNAPSRLNQSPSLAPVKRTYEQMEFPLLKKRKLDDDSDSPSFFEEKPEEPVVLALDPKGHEDDSYEARKSFLTKYFNKQPYPTRREIEKLAASLWLWKSDIASHFSNKRKKCVRDCEKYKPGVLLGFNMKELNKVKHEMDFDAEWLFENHDEKDSRVNASKTADKKLNLGKEDDSSSDSFENLEEESNESGSPFDPVFEVEPKISNDNPEEHVLKVIPEDASESEEKLDQKEDGSKYETIHLTEEPTKLMHNASDSEVDQDDVVEWKDGASPSESGPGSQQVSDFEDNTCEMKPGTWSDESSQSEDARSSKPAAKKKATMQGDREQLKWKNSSYGKVEGFWSKDQSQWKNASENDERLSNPQIEWQNSTIDSEDGEQFDNMTDGVAEPMHGSLAGVKLSSQQA

种属预测

种属预测:

score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。

Species
Results
Score
Rabbit
100
Pig
92
Horse
92
Dog
92
Bovine
83
Sheep
83
Chicken
83
Xenopus
64
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q9H2P0 作为底物

Site PTM Type Enzyme
S11 Phosphorylation
K32 Ubiquitination
K39 Ubiquitination
K65 Ubiquitination
S87 Phosphorylation
S98 Phosphorylation
K126 Ubiquitination
K144 Sumoylation
K144 Ubiquitination
S213 Phosphorylation
T258 Phosphorylation
K274 Sumoylation
K279 Sumoylation
S289 Phosphorylation
S292 Phosphorylation
R306 Methylation
S336 Phosphorylation
S346 Phosphorylation
R348 Methylation
S372 Phosphorylation
R385 Methylation
R391 Methylation
S393 Phosphorylation
K408 Methylation
K408 Sumoylation
S409 Phosphorylation
S411 Phosphorylation
S413 Phosphorylation
S415 Phosphorylation
S418 Phosphorylation
S424 Phosphorylation
S425 Phosphorylation
K427 Sumoylation
K427 Ubiquitination
K445 Ubiquitination
K600 Sumoylation
K606 Sumoylation
S607 Phosphorylation
S608 Phosphorylation
Y615 Phosphorylation
K616 Ubiquitination
K621 Ubiquitination
K658 Sumoylation
S678 Phosphorylation
K692 Ubiquitination
S709 Phosphorylation
K716 Methylation
K716 Sumoylation
K716 Ubiquitination
Y719 Phosphorylation
K731 Sumoylation
K731 Ubiquitination
S736 Phosphorylation
S738 Phosphorylation
S740 Phosphorylation
K745 Sumoylation
K757 Ubiquitination
K768 Ubiquitination
S769 Phosphorylation
T772 Phosphorylation
K773 Ubiquitination
Y774 Phosphorylation
K777 Ubiquitination
S805 Phosphorylation
K807 Ubiquitination
K819 Sumoylation
K835 Sumoylation
T861 Phosphorylation
S875 Phosphorylation
S876 Phosphorylation
S878 Phosphorylation
S904 Phosphorylation
K914 Ubiquitination
S921 Phosphorylation
S923 Phosphorylation
K930 Sumoylation
K935 Ubiquitination
S953 Phosphorylation
S955 Phosphorylation
S970 Phosphorylation
S982 Phosphorylation
S997 Phosphorylation
S1000 Phosphorylation
S1001 Phosphorylation
S1003 Phosphorylation
S1032 Phosphorylation
K1035 Acetylation
K1035 Sumoylation
K1042 Acetylation
K1042 Ubiquitination
S1058 Phosphorylation
S1067 Phosphorylation
S1071 Phosphorylation
S1091 Phosphorylation

研究背景

功能:

Potential transcription factor. May mediate some of the neuroprotective peptide VIP-associated effects involving normal growth and cancer proliferation.

细胞定位:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Widely expressed. Strong expression in heart, skeletal muscle, kidney and placenta. In brain, expression is stronger in the cerebellum and cortex regions. No expression detected in the colon. Strong increase of expression in colon and breast cancer tissues.

限制条款

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