Phospho-TTK (Thr676) Antibody - #AF8194

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产品: 磷酸化 TTK (Thr676) 抗体
货号: AF8194
描述: Rabbit polyclonal antibody to Phospho-TTK (Thr676)
应用: WB IHC
反应: Human, Mouse, Rat
预测: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken
蛋白号: P33981
RRID: AB_2840256

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   规格 价格 库存
 100ul RMB¥ 2800 现货
 200ul RMB¥ 3800 现货

货期: 当天发货

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实验方案
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IHC Protocol
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产品描述

来源:
Rabbit
应用:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
Phospho-TTK (Thr676) Antibody detects endogenous levels of TTK only when phosphorylated at Thr676.
RRID:
AB_2840256
引用格式: Affinity Biosciences Cat# AF8194, RRID:AB_2840256.
偶联:
Unconjugated.
纯化:
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

cancer/testis antigen 96; CT96; Dual specificity protein kinase TTK; ECSTY kinase; ESK; FLJ38280; hMPS1; Monopolar Spindle 1 Like 1; MPH1; Mps 1; MPS1L1; Phosphotyrosine Picked Threonine Kinase; Phosphotyrosine picked threonine-protein kinase; PYT; RP3-357D13.2; ttk; TTK Protein Kinase; TTK_HUMAN;

抗原和靶标

免疫原:

A synthesized peptide derived from human TTK around the phosphorylation site of Thr676.

基因/基因ID:
TTK(7272)

研究领域

· Cellular Processes > Cell growth and death > Cell cycle.   (View pathway)

文献引用

1). Design, synthesis and biological evaluation of a new class of 7H-pyrrolo[2,3-d]pyrimidine derivatives as Mps1 inhibitors for the treatment of breast cancer. European Journal of Medicinal Chemistry, 2023 (PubMed: 36370549) [IF=6.0]
2). Discovery of a potent and selective covalent threonine tyrosine kinase (TTK) inhibitor. Bioorganic chemistry, 2024 (PubMed: 38159497) [IF=4.5]

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