Phospho-CtIP (Ser664) Antibody - #AF8094

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产品: 磷酸化 CtIP (Ser664) 抗体
货号: AF8094
描述: Rabbit polyclonal antibody to Phospho-CtIP (Ser664)
应用: WB IHC
文献验证: IHC
反应: Human, Mouse, Rat
预测: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
蛋白号: Q99708
RRID: AB_2840157

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   规格 价格 库存
 100ul RMB¥ 2800 现货
 200ul RMB¥ 3800 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
Phospho-CtIP (Ser664) Antibody detects endogenous levels of CtIP only when phosphorylated at Ser664.
RRID:
AB_2840157
引用格式: Affinity Biosciences Cat# AF8094, RRID:AB_2840157.
偶联:
Unconjugated.
纯化:
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

COM1; COM1_HUMAN; CtBP interacting protein; CtBP-interacting protein; CtIP; DNA endonuclease RBBP8; JWDS; RBBP-8; RBBP8; Retinoblastoma-binding protein 8; Retinoblastoma-interacting protein and myosin-like; Rim; SAE2; SCKL2; Sporulation in the absence of SPO11 protein 2 homolog;

抗原和靶标

免疫原:

A synthesized peptide derived from human CtIP around the phosphorylation site of Ser664.

基因/基因ID:
RBBP8(5932)

研究领域

· Genetic Information Processing > Replication and repair > Homologous recombination.

文献引用

1). Reactive Oxygen Species Mediate Low Back Pain by Upregulating Substance P in Intervertebral Disc Degeneration. Oxidative Medicine and Cellular Longevity, 2021 (PubMed: 34093962)

Application: IHC    Species: Human    Sample:

Figure 3 ROS significantly induced the expression of substance P. (a) H2O2 significantly induced the expression of the SP gene in NPCs in a dose-dependent manner with RT-PCR expression. (b) Western blot analysis also verified the increase in SP after stimulation with H2O2 in a dose-dependent manner. (c) Administration of H2O2 into the IVDs of rats resulted in significant upregulation of the SP protein. (d) IHC analysis suggested a remarkable increase in SP protein levels in the NP after administration of 100 μM H2O2, while the expression of the SP protein in the sham surgery group was low (The data are shown as the mean ± SD. N = 3 ~ 5 for each group. ∗

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