Phospho-Ret (Tyr905) Antibody - #AF8055

>>赠JD卡 进行中>>
(2)   (3)  
产品: 磷酸化 Ret (Tyr905) 抗体
货号: AF8055
描述: Rabbit polyclonal antibody to Phospho-Ret (Tyr905)
应用: WB IF/ICC
文献验证: WB
反应: Human, Mouse, Rat, Monkey
预测: Pig, Zebrafish, Bovine, Sheep, Rabbit, Dog, Xenopus
蛋白号: P07949
RRID: AB_2840118

浏览相似产品>>

   规格 价格 库存
 100ul RMB¥ 2800 现货
 200ul RMB¥ 3800 现货

货期: 当天发货

联系销售
相关下载
MS Report
HPLC Report
MSDS
说明书
COA
实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:1000-3000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat, Monkey
克隆:
Polyclonal
特异性:
Phospho-Ret (Tyr905) Antibody detects endogenous levels of Ret only when phosphorylated at Tyr905.
RRID:
AB_2840118
引用格式: Affinity Biosciences Cat# AF8055, RRID:AB_2840118.
偶联:
Unconjugated.
纯化:
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

C ret; Cadherin family member 12; Cadherin related family member 16; CDHF 12; CDHF12; CDHR16; ELKS Fusion gene; HSCR 1; HSCR1; Hydroxyaryl protein kinase; MEN2A; MEN2B; MTC 1; MTC1; Multiple endocrine neoplasia and medullary thyroid carcinoma 1; Oncogene RET; Proto oncogene tyrosine protein kinase receptor ret; Proto-oncogene c-Ret; Proto-oncogene tyrosine-protein kinase receptor ret; PTC; RET; RET ELE1; Ret Proto oncogene; RET transforming sequence; RET_HUMAN; RET51; RET9; tyrosine-protein kinase receptor ret;

抗原和靶标

免疫原:

A synthesized peptide derived from human Ret around the phosphorylation site of Tyr905.

基因/基因ID:
RET(5979)

研究领域

· Human Diseases > Cancers: Overview > Pathways in cancer.   (View pathway)

· Human Diseases > Cancers: Specific types > Thyroid cancer.   (View pathway)

· Human Diseases > Cancers: Overview > Central carbon metabolism in cancer.   (View pathway)

文献引用

1). RET S409Y Germline Mutation and Associated Medullary Thyroid Carcinoma. THYROID, 2019 (PubMed: 31364476) [IF=5.8]

Application: WB    Species: human    Sample: HEK293 cells

Figure 2.| In vitro assays performed to characterize the RET9 S409Y mutation C. Western blotting to detect phosphorylation and activation of AKT and ERK pathways after transient transfection of HEK293 cells with RET9 S409Y. Protein lysates (10 µg) from HEK293 cells transfected with RET9 WT (negative control), C634Y, C618Y, (positive control), S409Y or untransfected HEK293 cells were separated by SDSPAGE and transferred to PVDF membranes (n= 4), which were incubated with anti‐RET (a), anti‐p‐RET (Y905; b), anti‐p‐AKT (d), anti‐p-ERK1/2 (T202/Y204; f), or antiactin (c; control for b and h; control for e and g) antibodies.
2). Selpercatinib attenuates bleomycin-induced pulmonary fibrosis by inhibiting the TGF-β1 signaling pathway. Biochemical pharmacology, 2024 (PubMed: 38762147) [IF=5.3]

限制条款

产品的规格、报价、验证数据请以官网为准，官网链接：www.affbiotech.com | www.affbiotech.cn（简体中文）| www.affbiotech.jp（日本語）

产品的数据信息为Affinity所有，未经授权不得收集Affinity官网数据或资料用于商业用途，对抄袭产品数据的行为我们将保留诉诸法律的权利。

产品相关数据会因产品批次、产品检测情况随时调整，如您已订购该产品，请以订购时随货说明书为准，否则请以官网内容为准，官网内容有改动时恕不另行通知。

Affinity保证所销售产品均经过严格质量检测。如您购买的商品在规定时间内出现问题需要售后时，请您在Affinity官方渠道提交售后申请。

产品仅供科学研究使用。不用于诊断和治疗。 

产品未经授权不得转售。

Affinity Biosciences将不会对在使用我们的产品时可能发生的专利侵权或其他侵权行为负责。Affinity Biosciences, Affinity Biosciences标志和所有其他商标所有权归Affinity Biosciences LTD.