产品: SFXN4 抗体
货号: AF0580
描述: Rabbit polyclonal antibody to SFXN4
应用: WB IF/ICC
反应: Human
分子量: 37kDa; 38kD(Calculated).
蛋白号: Q6P4A7
RRID: AB_2834289

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   规格 价格 库存
 50ul RMB¥ 1250 现货
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 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
克隆:
Polyclonal
特异性:
SFXN4 Antibody detects endogenous levels of total SFXN4.
RRID:
AB_2834289
引用格式: Affinity Biosciences Cat# AF0580, RRID:AB_2834289.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

BCRM1; Breast cancer resistance marker 1; SFXN 4; Sideroflexin 4;

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
描述:
Sfxn4 Potential iron transporter. Belongs to the sideroflexin family. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
序列:
MSLEQEEETQPGRLLGRRDAVPAFIEPNVRFWITERQSFIRRFLQWTELLDPTNVFISVESIENSRQLLCTNEDVSSPASADQRIQEAWKRSLATVHPDSSNLIPKLFRPAAFLPFMAPTVFLSMTPLKGIKSVILPQVFLCAYMAAFNSINGNRSYTCKPLERSLLMAGAVASSTFLGVIPQFVQMKYGLTGPWIKRLLPVIFLVQASGMNVYMSRSLESIKGIAVMDKEGNVLGHSRIAGTKAVRETLASRIVLFGTSALIPEVFTYFFKRTQYFRKNPGSLWILKLSCTVLAMGLMVPFSFSIFPQIGQIQYCSLEEKIQSPTEETEIFYHRGV

翻译修饰 - Q6P4A7 作为底物

Site PTM Type Enzyme
S2 Acetylation
S2 Phosphorylation
K90 Ubiquitination
K106 Ubiquitination
C159 S-Nitrosylation
K160 Ubiquitination
K197 Acetylation
K197 Ubiquitination
S209 Phosphorylation
K223 Ubiquitination
K230 Ubiquitination
S324 Phosphorylation

研究背景

功能:

Mitochondrial amino-acid transporter (By similarity). Does not act as a serine transporter: not able to mediate transport of serine into mitochondria.

细胞定位:

Mitochondrion inner membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
蛋白家族:

Belongs to the sideroflexin family.

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